Extracts well tolerated by skin cells
LaboratoryHydro-alcoholic extracts of leaves and aerial partsKeratinocytes, fibroblasts, melanocytesApplication on human skin
The leaf extract inhibits 89% in the antioxidant test, against 95% for the reference. It induces no notable cytotoxicity on the normal skin cell lines tested. Erythema values decrease after application on human skin; the abstract does not detail the protocol6.
Protection of collagen fibers against UVA in culture
LaboratoryBasil extract containing rosmarinic acidHuman dermal fibroblastsRepeated UVA
The extract and rosmarinic acid reduce reactive oxygen species and carbonylated proteins, and restore type I collagen synthesis and the number of collagen fibers in irradiated fibroblasts7.
Effects described, with no quantified clinical result
Review2026 narrative reviewStudies from 1999 to 2025
The review reports antioxidant, antimicrobial, moisturizing and protective effects attributed to flavonoids, phenolic acids and terpenes. Its abstract gives no figure from a clinical trial8.