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Zinc oxide is a white inorganic oxide, listed in CosIng as a UV filter, colorant (CI 77947) and skin protecting agent1. European regulation allows it as a UV filter up to 25%, including in nano form, in applications that cannot expose the lungs by inhalation (Annex VI, entries 30 and 30a)2. The sun protection factor depends on the formula tested56.
Entry from our cosmetic ingredient glossary. Regulatory data from the European Commission's CosIng database1 and Regulation (EC) 1223/20092. Copy the identifiers in one click for your files.
Each result shows the protocol and the level of evidence. The higher the level, the better the result carries over to a finished formula.
At 5%, zinc oxide attenuates UVA above 360 nm better than titanium dioxide. At comparable sun protection factor, products with zinc oxide or avobenzone have clearly higher UVA protection factors than those with titanium dioxide4.
Formulas rich in zinc oxide often give a lower in vitro factor than the in vivo factor. The authors explain this by density (1.3 to 1.7 g/ml versus about 1.0 for an organic filter emulsion): at equal weight, the deposited film is thinner. Preliminary tests at equal volume correlate better; further evidence is needed5.
Variability between laboratories is proportional to the factor: the higher it is, the greater the spread. The authors judge it greater than what the public and regulators expect6. A product's factor therefore depends on its formula and the test method, not on a single filter.
All studies agree: the vast majority of nanoparticles stay on the skin surface. Conclusions on passage into living skin are mixed, because protocols differ widely7. Most authors find no penetration into the living layers; passage through damaged skin is not excluded and needs studies8.
Zinc oxide is practically non-toxic in animals and shows no carcinogenic potential. A no-effect dose of 268.4 mg/kg/day was retained; the maximum estimated systemic exposure for a sunscreen is 0.6 mg/kg/day, a safety margin of 448.2 at the lowest. The authors conclude it is safe to use within the 25% regulatory limit in force in Korea9.
According to this review, insoluble titanium dioxide and zinc oxide nanoparticles do not cross human skin, and no difference in safety profile appears between micro and nano forms10. The authors work for a cosmetics manufacturer.
For the 6 organic filters tested (avobenzone, oxybenzone, octocrylene, homosalate, octisalate, octinoxate), mean maximum plasma concentrations exceed 0.5 ng/mL, the FDA threshold, from the first day after a single application11. The trial measures absorption, not an effect on health, and does not cover zinc oxide.
This page summarizes published literature on a cosmetic ingredient. It does not describe the effect of a finished product, which depends on its formula, and it is not medical advice. Zinc oxide is a UV filter: the protection factor of a product depends on its whole formula and the measurement method, not on a single ingredient, and no factor is promised here. Several studies are authored by industry, as the source list indicates.
No trial cited compares several concentrations in the same formula. The model UVA study uses 5% zinc oxide4, and a review discusses formulas at 10-25%5. The regulation sets 25% as the maximum, standard and nano forms added together2. The factor obtained depends on the formula tested, not on the level alone.
Our white label catalog includes 7 formulas with zinc oxide: the key active in 3 of them, a supporting ingredient in the others. Every category can be customized (formula, fragrance, packaging).
Key active in a diaper cream and a solid deodorant; mineral filter, with titanium dioxide, in the catalog sun care products.
In our formulas, it is most often paired with
Aloe vera 4Titanium dioxide 3Sweet almond oil 3Argan oil 3Vitamin E 3The choice between mineral and organic filters is made formula by formula. Here is what the sources say, with no promised factor.
| Zinc oxide | Titanium dioxide | Organic filters | |
|---|---|---|---|
| Nature | Inorganic oxide1 | Inorganic oxide12 | Organic molecules (avobenzone, octocrylene, homosalate...)11 |
| Annex VI | Entries 30 and 30a (nano): 25%2 | Entries 27 and 27a (nano): 25%2 | One entry per filter, each with its own limit2 |
| UVA in the lab | At 5%, good attenuation above 360 nm4 | At 5%, lower attenuation: does not replace zinc oxide or avobenzone for a high UVA level4 | Photostabilized avobenzone at 3%: also better than titanium dioxide at 5%4 |
| Inhalation | No application exposing the lungs2 | No application exposing the lungs2 | Condition specific to each entry, for example "not to be used in sprays" for tris-biphenyl triazine2 |
| Point of attention | In vitro factor sometimes underestimated at 10-25%5 | Powders with ≥ 1% of particles ≤ 10 µm: Annex III, entry 3212 | Passage into blood measured for 6 filters at maximal use11 |
Peer-reviewed studies and official regulatory sources, checked on November 3, 2026.
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