Mouse skin barrier: an unfavorable effect
LaboratoryMiceBarrier damaged by adhesive tape strippingComparison of several oils
Mustard, olive and soybean oils all delayed barrier recovery, compared with control skin or skin treated with a reference ointment. Sunflower oil accelerated it3. The model covers an already damaged barrier.
The ratio of linoleic to oleic acid matters
Review2018 reviewNatural oils and the barrier
An oil with a higher linoleic/oleic ratio has a better potential for the barrier; an excess of oleic acid can harm it5. Soybean is not among the oils this review details.
A review of 27 clinical studies on 17 oils, including soybean
Review2022 review27 studies, 17 oils
On unaffected skin, an oil rich in oleic acid does not necessarily react badly; on weakened skin, an oil rich in oleic and low in linoleic acid can add damage to the stratum corneum. Frequency and duration of use also matter4. The authors give no conclusion specific to soybean in their abstract.
A review of skin applications of several oils
Review2017 reviewIncluding soybean oil
The review brings together data on the skin application of nineteen vegetable oils and butters, including soybean6.