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Copaiba essential oil is the volatile fraction of the resin of Copaifera officinalis1. Its main constituent is often β-caryophyllene, from 19.7 to 57.5% depending on the species4, named as a fragrance allergen in Annex III2. The oil is not named, and studies on human skin are rare5.
Entry from our cosmetic ingredient glossary. Regulatory data from the European Commission's CosIng database1 and from Regulation (EU) 2023/15452. Copy the identifiers in one click for your files.
Each result shows the protocol and the level of evidence. The higher the level, the better the result carries over to a finished formula.
β-caryophyllene makes up 57.5% of C. multijuga oil, 19.7% of C. cearensis oil and 40.9% of C. reticulata oil. The acidic diterpenes also differ: copalic acid (6.2%) in C. multijuga, clorechinic and hardwickiic acids in C. cearensis4.
The essential oil has 48 substances, of which 14 main ones account for 95.8% of the total. cis-Thujopsene makes up nearly 47%5. Reviews describe the same families: volatile sesquiterpenes and acidic diterpenes78.
The review of in vitro and in vivo studies concludes that the toxic effects of copaiba oils and their constituents are poorly known, despite their traditional use9.
The oleoresin and its volatile and resinous fractions increase neither DNA damage nor micronuclei. This test covers genotoxicity after ingestion: it says nothing about skin tolerance10.
The main constituent oxidizes to β-caryophyllene oxide: the authors recommend adding antioxidants, working at low oxygen levels and protecting the product through packaging11. In mice, repeated applications of β-caryophyllene at 10 mg/mL cause itching, thickening of the epidermis and a rise in IgE: the sensitizing potential deserves attention12.
The area affected by blemishes decreases clearly more with the copaiba gel than with placebo, which also has an effect. The study aimed at a medical use: we only keep the result on the look of the skin, and we found no second study to confirm it5.
With the nanoemulsion, β-caryophyllene reaches the dermis, which the crude oil does less well. The delivery system therefore affects penetration13. This is a penetration measurement only: it does not demonstrate a cosmetic effect.
This page summarizes published literature on a cosmetic ingredient. It does not describe the effect of a finished product, which depends on its formula, and it is not medical advice. Evidence is flagged by level: clinical trial, review or laboratory.
No formula in our white label catalog features copaiba oil yet. Our formulation lab can add it to a custom formula or to a catalog formula. Its common uses:
Targeted care gels and serums: a controlled trial exists at 1%, but it remains isolated.
Massage oils, balms and body milks with a woody and spicy note, soaps.
Hair oils and leave-in care; we found no published study on hair with this oil.
Four oils with woody notes, often confused in purchasing sheets. Their chemistry differs, and so does their labeling status.
| Copaiba | Patchouli | West Indian sandalwood | Rosewood | |
|---|---|---|---|---|
| Dominant constituents | β-caryophyllene (19.7 to 57.5% depending on the species)4 | Patchouli alcohol (about 28% in the oil studied)14 | Valerianol, elemol, eudesmol isomers, caryophyllene15 | Linalool (93.6% in one oil studied)16 |
| Annex III | Oil not named; beta-caryophyllene named (line 332)2 | Oil named (line 365)2 | Oil not named3 | Oil not named; linalool named (line 84)3 |
Peer-reviewed studies and official regulatory sources, checked on November 3, 2026.
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