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Oregano (Origanum vulgare, Lamiaceae) is an aromatic plant whose oil is mostly carvacrol or thymol depending on the chemotype45. Its dried, ground leaf has the INCI name ORIGANUM VULGARE LEAF, which CosIng classifies as skin conditioning1. Cosmetic studies cover the oil, in the laboratory, and also report cases of irritation710. No trial on the powder was retained.
Entry from our cosmetic ingredient glossary. Data from the European Commission's CosIng database1, consolidated Regulation (EC) No 1223/20092 and Regulation (EU) 2023/15453. Copy the identifiers in one click for your files.
Each result shows the protocol and the level of evidence. The higher the level, the better the result carries over to a finished formula.
The oil compound content ranges from 0.03% to 4.6%. Depending on the share of cymyl, sabinyl or linalool and linalyl acetate compounds, three chemotypes are defined. The cymyl and acyclic pathways dominate in Mediterranean climates, the sabinyl pathway in continental climates4.
The carvacrol-rich genotype has a less complex profile and more carvacrol than the thymol-rich one. The oils show strong antimicrobial activity in vitro5.
Oregano oil is rich in thymol and carvacrol, compounds described as antioxidant and antimicrobial; they are also present in the extracts6.
The oil reduces reactive oxygen species, ICAM-1, iNOS, COX-2, the DNA damage marker 8-OHdG and the metalloproteinases MMP-1 and MMP-12, and promotes cell migration in a scratch test. A cell culture result on the oil, not on the powder7.
The review ties the cosmeceutical interest of the oil to thymol and carvacrol. Work mostly covers antimicrobial activity and micro- and nanoemulsion formulations for topical application8.
Origanoside reduces the expression of MITF, tyrosinase and TRP-2 in culture; in mice, the skin lightens. A single isolated molecule, no human trial: the result applies neither to the powder nor to a finished product9.
A 2020 publication describes an irritation reaction of the skin after an unusual use of oregano essential oil10. An isolated case: it gives no frequency.
Concordant results at 10 and 25% are most frequent with ginger (7 participants), nutmeg (5) and oregano (4). Only three participants show a response judged relevant, all spices combined11.
This page summarizes published literature on a cosmetic ingredient. It does not describe the effect of a finished product, which depends on its formula, and it is not medical advice. Evidence is flagged by level: clinical trial, review or laboratory.
No formula in our white label catalog features oregano yet. Our formulation lab can add it to a custom formula or to a catalog formula. Its common uses:
Traditional soaps and plant powder scrubs, aromatic massage oils.
Hair care with aromatic plants, as an extract or a supporting powder.
Peer-reviewed studies and official regulatory sources, checked on November 3, 2026.
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