Less sebum and more hydrated skin in 21 days
Clinical trialSalicylic acid gel21 days42 volunteersTwice a dayProspective single-center study
In volunteers with oily or combination, blemish-prone skin, sebum fell by 23.65%, hydration rose by 40.5% and water loss dropped by 49.26%. 5% of participants reported mild, temporary itching. The concentration is not given in the abstract7.
Better texture, redness and barrier in 28 days
Clinical trialCleanser with salicylic acid, glucuronolactone and ceramides28 days42 volunteers
Significant improvement in the barrier (water loss), redness, hydration and skin texture, with no adverse effect. The formula also contains ceramides: the effect of salicylic acid alone is not isolated8.
Less stratum corneum in one week
Clinical trial2 to 12%1 week23 volunteersHealthy skin, vehicle only on the other side
Treated sites had less stratum corneum, with no change in the living epidermis. The authors suggest that salicylic acid promotes desquamation by dissolving the cement between cells5.