{"id":57065,"date":"2026-11-02T22:01:27","date_gmt":"2026-11-02T22:01:27","guid":{"rendered":"https:\/\/carmelcosmeticslabs.com\/?page_id=57065"},"modified":"2026-11-09T07:29:38","modified_gmt":"2026-11-09T07:29:38","slug":"alfa-arbutina","status":"publish","type":"page","link":"https:\/\/carmelcosmeticslabs.com\/es\/glosario-ingredientes-cosmeticos\/alfa-arbutina\/","title":{"rendered":"Alfa-arbutina"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"57065\" class=\"elementor elementor-57065 elementor-54200 elementor-bc-flex-widget\" data-elementor-post-type=\"page\">\n\t\t\t\t<div data-particle_enable=\"false\" data-particle-mobile-disabled=\"false\" class=\"elementor-element elementor-element-a5a3ec4 e-flex e-con-full e-con e-parent\" data-id=\"a5a3ec4\" data-element_type=\"container\" data-e-type=\"container\" id=\"ing-alpha-arbutine\">\n\t\t\t\t<div class=\"elementor-element elementor-element-dadaf69 elementor-widget elementor-widget-html\" 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svg{width:20px;height:20px;flex:none;color:var(--deep-muted)}\n@media (max-width:900px){.ig .c-grid{grid-template-columns:1fr;gap:32px}}\n@media (max-width:560px){.ig form.lead{grid-template-columns:1fr;padding:20px}}\n@media (prefers-reduced-motion:reduce){.ig *,.ig *::details-content,.ig .pop,.ig .scrim,.ig .fab{transition:none!important}}\n.ig .hero h1.h1-long{font-size:clamp(38px,4.6vw,60px);line-height:1.02}\n.ig .pins-list{display:none;list-style:none;margin:0 0 20px;padding:0;order:-1}\n.ig .pins-list li{display:flex;gap:12px;align-items:baseline;margin-bottom:10px;font-size:14px;line-height:1.4;color:var(--ink-2)}\n.ig .pins-list strong{font:600 22px\/1 var(--f-display);color:var(--teal-strong);min-width:72px}\n.ig .scale.dense{display:flex;flex-direction:column;padding-top:0}\n.ig .scale.dense .pins-list{display:block}\n.ig .scale.dense .track .pin{display:none}\n@media (max-width:560px){.ig .scale{display:flex;flex-direction:column;padding-top:0}.ig .pins-list{display:block}.ig .track .pin{display:none}}\n<\/style>\n<div class=\"ig\" data-ing=\"alpha-arbutine\" lang=\"es\" data-copy=\"Copiar\" data-copied=\"Copiado\">\n<nav class=\"crumbs wrap\" aria-label=\"Ruta de navegaci\u00f3n\"><ol>\n  <li><a href=\"https:\/\/carmelcosmeticslabs.com\/es\/\">Inicio<\/a><\/li><li><a href=\"https:\/\/carmelcosmeticslabs.com\/es\/glosario-ingredientes-cosmeticos\/\">Glosario de ingredientes<\/a><\/li><li aria-current=\"page\">Alfa-arbutina<\/li><\/ol><\/nav>\n<header class=\"wrap hero\" id=\"top\">\n  <div class=\"hero-copy\">\n    <h1>Alfa-arbutina<\/h1>\n    <p class=\"brief\">La alfa-arbutina es un gluc\u00f3sido de la hidroquinona obtenido por s\u00edntesis enzim\u00e1tica<a class=\"ref\" href=\"#src-3\">3<\/a>. En el laboratorio, frena la formaci\u00f3n de melanina<a class=\"ref\" href=\"#src-4\">4<\/a> y act\u00faa con m\u00e1s intensidad que la beta-arbutina sobre la tirosinasa humana<a class=\"ref\" href=\"#src-5\">5<\/a>. La evidencia cl\u00ednica sigue siendo escasa. La UE la limita al 2% en cremas faciales y al 0.5% en lociones corporales<a class=\"ref\" href=\"#src-2\">2<\/a>.<\/p>\n    <div class=\"byline\"><span class=\"avatar\" aria-hidden=\"true\">ME<\/span>\n      <span><strong>Mohamed El Hjouji<\/strong>Fundador y director ejecutivo \u00b7 Actualizado <time datetime=\"2026-11-02\">2 de noviembre de 2026<\/time> \u00b7 Tiempo de lectura 8 min<\/span><\/div>\n    <div class=\"actions\">\n      <a class=\"btn\" href=\"#consultation\">Crear un producto con alfa-arbutina <span class=\"knob\" aria-hidden=\"true\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.8\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/span><\/a>\n      <a class=\"btn-ghost\" href=\"#recherche\">Consultar los estudios<\/a>\n    <\/div>\n  <\/div>\n  <figure class=\"hero-photo\"><img fetchpriority=\"high\" src=\"https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/alpha-arbutine-ingredient-cosmetique-carmel.webp\" srcset=\"https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/alpha-arbutine-ingredient-cosmetique-carmel-300x224.webp 300w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/alpha-arbutine-ingredient-cosmetique-carmel-441x329.webp 441w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/alpha-arbutine-ingredient-cosmetique-carmel-768x574.webp 768w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/alpha-arbutine-ingredient-cosmetique-carmel-990x740.webp 990w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/alpha-arbutine-ingredient-cosmetique-carmel-1024x765.webp 1024w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/alpha-arbutine-ingredient-cosmetique-carmel.webp 1400w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/alpha-arbutine-ingredient-cosmetique-carmel.webp 1400w\" sizes=\"(max-width:900px) 92vw, 46vw\" width=\"1400\" height=\"1046\" alt=\"Polvo blanco de alfa-arbutina, vista macro sobre una superficie de cer\u00e1mica verde salvia\" fetchpriority=\"high\" decoding=\"async\" title=\"| Carmel Cosmetics Labs\"><\/figure>\n<\/header>\n<div class=\"bar\" id=\"bar\"><div class=\"wrap bar-in\">\n  <nav aria-label=\"En esta p\u00e1gina\"><ul><li><a href=\"#identite\">Identidad<\/a><\/li><li><a href=\"#recherche\">Investigaci\u00f3n<\/a><\/li><li><a href=\"#concentrations\">Concentraciones<\/a><\/li><li><a href=\"#produits\">Productos<\/a><\/li><li><a href=\"#comparatif\">Comparaci\u00f3n<\/a><\/li><li><a href=\"#faq\">Preguntas<\/a><\/li><li><a href=\"#plus\">Lecturas<\/a><\/li><li><a href=\"#sources\">Fuentes<\/a><\/li><\/ul><\/nav>\n  <a class=\"btn sm\" href=\"#consultation\" tabindex=\"-1\">Crear mi producto <span class=\"knob\" aria-hidden=\"true\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.8\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/span><\/a><\/div>\n  <span class=\"bar-prog\" id=\"prog\" aria-hidden=\"true\"><\/span><\/div>\n<section class=\"sec\" id=\"identite\" aria-labelledby=\"h-id\"><div class=\"wrap id-grid\">\n  <div><h2 class=\"h2\" id=\"h-id\">Alfa-arbutina de un vistazo<\/h2>\n  <p class=\"lede\">Entrada de nuestro <a class=\"txt-link\" href=\"https:\/\/carmelcosmeticslabs.com\/es\/glosario-ingredientes-cosmeticos\/\">glosario de ingredientes cosm\u00e9ticos<\/a>. Datos de la base CosIng de la Comisi\u00f3n Europea<a class=\"ref\" href=\"#src-1\">1<\/a>, del Reglamento (UE) 2024\/996<a class=\"ref\" href=\"#src-2\">2<\/a> y del dictamen del comit\u00e9 cient\u00edfico SCCS<a class=\"ref\" href=\"#src-3\">3<\/a>. Copie los identificadores con un clic para sus documentos.<\/p><\/div>\n  <dl class=\"spec\"><div><dt>Nombre INCI<\/dt><dd><span class=\"\">ALPHA-ARBUTIN<\/span><button class=\"copy\" type=\"button\" data-copy=\"ALPHA-ARBUTIN\" aria-label=\"Copiar: Nombre INCI\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><rect x=\"9\" y=\"9\" width=\"11\" height=\"11\" rx=\"2\"\/><path d=\"M5 15V5a2 2 0 0 1 2-2h8\"\/><\/svg>Copiar<\/button><\/dd><\/div><div><dt>Otros nombres<\/dt><dd>4-Hidroxifenil-alfa-D-glucopiran\u00f3sido<small>Is\u00f3mero alfa de la arbutina<a class=\"ref\" href=\"#src-3\">3<\/a><\/small><\/dd><\/div><div><dt>N\u00famero CAS<\/dt><dd><span class=\"num\">84380-01-8<\/span><button class=\"copy\" type=\"button\" data-copy=\"84380-01-8\" aria-label=\"Copiar: N\u00famero CAS\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><rect x=\"9\" y=\"9\" width=\"11\" height=\"11\" rx=\"2\"\/><path d=\"M5 15V5a2 2 0 0 1 2-2h8\"\/><\/svg>Copiar<\/button><\/dd><\/div><div><dt>N\u00famero CE<\/dt><dd><span class=\"num\">617-561-8<\/span><button class=\"copy\" type=\"button\" data-copy=\"617-561-8\" aria-label=\"Copiar: N\u00famero CE\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><rect x=\"9\" y=\"9\" width=\"11\" height=\"11\" rx=\"2\"\/><path d=\"M5 15V5a2 2 0 0 1 2-2h8\"\/><\/svg>Copiar<\/button><\/dd><\/div><div><dt>F\u00f3rmula<\/dt><dd class=\"num\">C\u2081\u2082H\u2081\u2086O\u2087<small>Gluc\u00f3sido de la hidroquinona<a class=\"ref\" href=\"#src-3\">3<\/a><\/small><\/dd><\/div><div><dt>Origen<\/dt><dd>S\u00edntesis enzim\u00e1tica<small>Glucosilaci\u00f3n de la hidroquinona; la beta-arbutina est\u00e1 presente en las hojas y la corteza de numerosas plantas<a class=\"ref\" href=\"#src-3\">3<\/a><\/small><\/dd><\/div><div><dt>Funciones CosIng<\/dt><dd>Antioxidante, aclarador de la piel<small>Tambi\u00e9n act\u00faa como acondicionador de la piel<a class=\"ref\" href=\"#src-1\">1<\/a><\/small><\/dd><\/div><div><dt>Situaci\u00f3n en la UE<\/dt><dd>Restringida<small>Anexo III, n.\u00ba 377: 2% en cremas faciales, 0.5% en lociones corporales. La hidroquinona debe mantenerse al nivel de trazas inevitables<a class=\"ref\" href=\"#src-2\">2<\/a><\/small><\/dd><\/div><div><dt>Al\u00e9rgeno de declaraci\u00f3n obligatoria<\/dt><dd>No<\/dd><\/div><div><dt>Seguridad<\/dt><dd>Considerada segura a las concentraciones permitidas<small>Dictamen del SCCS de 31 de enero de 2023, incluida la exposici\u00f3n acumulada con arbutina<a class=\"ref\" href=\"#src-3\">3<\/a><\/small><\/dd><\/div><\/dl><\/div><\/section>\n<section class=\"sec research\" id=\"recherche\" aria-labelledby=\"h-r\"><div class=\"wrap\">\n  <div class=\"r-head\"><div><h2 class=\"h2\" id=\"h-r\">Qu\u00e9 dice la investigaci\u00f3n<\/h2>\n  <p class=\"lede\">Cada resultado indica el protocolo y el nivel de evidencia. Cuanto mayor sea el nivel, m\u00e1s aplicable ser\u00e1 el resultado a una f\u00f3rmula acabada.<\/p><\/div><\/div>\n  <div class=\"r-tools\"><div class=\"seg\" role=\"group\" aria-label=\"Filtrar por \u00e1rea\" id=\"rfilter\"><button type=\"button\" aria-pressed=\"true\" data-d=\"all\">Todos <span>6<\/span><\/button><button type=\"button\" aria-pressed=\"false\" data-d=\"visage\">Rostro <span>3<\/span><\/button><button type=\"button\" aria-pressed=\"false\" data-d=\"securite\">Seguridad <span>2<\/span><\/button><button type=\"button\" aria-pressed=\"false\" data-d=\"derm\">Expertos <span>1<\/span><\/button><\/div><div class=\"legend\" aria-label=\"Niveles de evidencia\"><span class=\"lvl\"><i class=\"dot c\"><\/i>Ensayo cl\u00ednico<\/span><span class=\"lvl\"><i class=\"dot r\"><\/i>Revisi\u00f3n o consenso<\/span><span class=\"lvl\"><i class=\"dot v\"><\/i>Laboratorio<\/span><\/div><\/div>\n  <div class=\"domain\" data-d=\"visage\"><h3>Piel del rostro<span>Cuidado de la piel<\/span><\/h3><div class=\"finds\"><article class=\"find\"><div class=\"find-top\"><h4>Menos melanina en un modelo de piel humana<\/h4><span class=\"lvl\"><i class=\"dot v\"><\/i>Laboratorio<\/span><\/div><div class=\"meta\"><span>0.5 mM en c\u00e9lulas; 250 \u00b5g en piel reconstruida<\/span><span>C\u00e9lulas de melanoma humano<\/span><span>Estudio del fabricante<\/span><\/div><p>La s\u00edntesis de melanina disminuye al 76% de la de las c\u00e9lulas de control y al 40% en el modelo de piel, sin toxicidad celular. Son resultados de laboratorio, no un efecto demostrado en piel viva<a class=\"ref\" href=\"#src-4\">4<\/a>.<\/p><\/article><article class=\"find\"><div class=\"find-top\"><h4>Mayor potencia que la beta-arbutina sobre la tirosinasa<\/h4><span class=\"lvl\"><i class=\"dot v\"><\/i>Laboratorio<\/span><\/div><div class=\"meta\"><span>Tirosinasa humana y de rat\u00f3n<\/span><span>Dos estudios de laboratorio<\/span><span>Estudios de fabricantes<\/span><\/div><p>En la tirosinasa humana, la constante de inhibici\u00f3n de la alfa-arbutina es 20 veces menor que la de la arbutina: la inhibici\u00f3n es m\u00e1s intensa<a class=\"ref\" href=\"#src-5\">5<\/a>. En la tirosinasa de melanoma de rat\u00f3n, es unas 10 veces m\u00e1s activa (IC50 de 0.48 mM), pero no inhibe la tirosinasa de hongos: el resultado depende de la enzima evaluada<a class=\"ref\" href=\"#src-6\">6<\/a>.<\/p><\/article><article class=\"find\"><div class=\"find-top\"><h4>Un gel experimental evaluado en voluntarios<\/h4><span class=\"lvl\"><i class=\"dot c\"><\/i>Ensayo cl\u00ednico<\/span><\/div><div class=\"meta\"><span>Gel con etosomas<\/span><span>Voluntarios, n\u00famero no indicado en el resumen<\/span><\/div><p>La formulaci\u00f3n mejora el \u00edndice de melanina, la hidrataci\u00f3n y la elasticidad de la piel. El resumen no indica el tama\u00f1o de la muestra ni los valores, y la f\u00f3rmula es experimental: no se a\u00edsla el efecto de la alfa-arbutina por s\u00ed sola<a class=\"ref\" href=\"#src-7\">7<\/a>.<\/p><\/article><\/div><\/div><div class=\"domain\" data-d=\"securite\"><h3>Evaluaci\u00f3n de seguridad<span>SCCS<\/span><\/h3><div class=\"finds\"><article class=\"find\"><div class=\"find-top\"><h4>Segura hasta el 2% en cremas faciales y el 0.5% en lociones corporales<\/h4><span class=\"lvl\"><i class=\"dot r\"><\/i>Dictamen del SCCS<\/span><\/div><div class=\"meta\"><span>SCCS\/1642\/22<\/span><span>31 de enero de 2023<\/span><\/div><p>El comit\u00e9 considera segura la alfa-arbutina a estas concentraciones, tambi\u00e9n cuando se usan conjuntamente, y considera que la exposici\u00f3n acumulada con arbutina no supone un riesgo. La hidroquinona debe mantenerse al nivel de trazas inevitables<a class=\"ref\" href=\"#src-3\">3<\/a>. El Reglamento (UE) 2024\/996 recoge estos l\u00edmites<a class=\"ref\" href=\"#src-2\">2<\/a>.<\/p><\/article><article class=\"find\"><div class=\"find-top\"><h4>Baja absorci\u00f3n cut\u00e1nea<\/h4><span class=\"lvl\"><i class=\"dot v\"><\/i>Laboratorio<\/span><\/div><div class=\"meta\"><span>In vitro<\/span><span>Piel humana, 3 donantes<\/span><span>Piel congelada durante 8 d\u00edas<\/span><\/div><p>La absorci\u00f3n cut\u00e1nea total alcanza el 0.27 \u00b1 0.13% de la dosis. El SCCS utiliza un 0.53% en sus c\u00e1lculos y se\u00f1ala el reducido n\u00famero de donantes<a class=\"ref\" href=\"#src-3\">3<\/a>.<\/p><\/article><\/div><\/div><div class=\"domain\" data-d=\"derm\"><h3>Opini\u00f3n de los expertos<span>Dermatolog\u00eda<\/span><\/h3><div class=\"finds\"><article class=\"find\"><div class=\"find-top\"><h4>Una alternativa cosm\u00e9tica que requiere ensayos de calidad<\/h4><span class=\"lvl\"><i class=\"dot r\"><\/i>Revisi\u00f3n<\/span><\/div><div class=\"meta\"><span>Revisiones bibliogr\u00e1ficas<\/span><span>2016 y 2021<\/span><\/div><p>La arbutina y sus derivados, el \u00e1cido k\u00f3jico y la nicotinamida se desarrollaron como alternativas cosm\u00e9ticas a agentes de uso m\u00e9dico con efectos secundarios<a class=\"ref\" href=\"#src-9\">9<\/a>. Una revisi\u00f3n de 2021 considera que siguen siendo necesarios ensayos de calidad, con muestras m\u00e1s amplias, para confirmar la eficacia y la seguridad de la alfa-arbutina<a class=\"ref\" href=\"#src-8\">8<\/a>.<\/p><\/article><\/div><\/div>\n  <p class=\"frame\">Esta ficha resume la bibliograf\u00eda publicada sobre un ingrediente cosm\u00e9tico. No describe el efecto de un producto acabado, que depende de su f\u00f3rmula, ni sustituye el asesoramiento m\u00e9dico. La evidencia sobre la alfa-arbutina procede principalmente de estudios de laboratorio; los ensayos cl\u00ednicos en piel sin alteraciones son escasos y los estudios publicados suelen abordar usos m\u00e9dicos, que no recogemos aqu\u00ed. Varios estudios fueron realizados por fabricantes; se indica en las fuentes.<\/p><\/div><\/section>\n<section class=\"sec\" id=\"concentrations\" aria-labelledby=\"h-c\"><div class=\"wrap dose\">\n  <div><h2 class=\"h2\" id=\"h-c\">Concentraciones utilizadas en los estudios<\/h2><p class=\"lede\">Ninguno de los ensayos citados especifica la concentraci\u00f3n evaluada sobre la piel. Las concentraciones de referencia son las evaluadas por el SCCS y fijadas por el reglamento: 2% en cremas faciales y 0.5% en lociones corporales<a class=\"ref\" href=\"#src-3\">3<\/a><a class=\"ref\" href=\"#src-2\">2<\/a>.<\/p><\/div>\n  <div class=\"scale\" role=\"img\" aria-label=\"Escala de 0 a 3%: l\u00edmite del 0.5% en lociones corporales y del 2% en cremas faciales\"><div class=\"track\"><div class=\"band\" style=\"left:16.6667%;width:50%\"><\/div>\n  <div class=\"pin\" style=\"left:16.6667%\"><strong class=\"num\">0.5%<\/strong><span>L\u00edmite en lociones corporales<a class=\"ref\" href=\"#src-2\">2<\/a><\/span><\/div><div class=\"pin\" style=\"left:66.6667%\"><strong class=\"num\">2%<\/strong><span>L\u00edmite en cremas faciales<a class=\"ref\" href=\"#src-2\">2<\/a><\/span><\/div><div class=\"ticks\"><span class=\"tick num\" style=\"left:0%\">0%<\/span><span class=\"tick num\" style=\"left:16.6667%\">0.5<\/span><span class=\"tick num\" style=\"left:33.3333%\">1<\/span><span class=\"tick num\" style=\"left:50%\">1.5<\/span><span class=\"tick num\" style=\"left:66.6667%\">2<\/span><span class=\"tick num\" style=\"left:83.3333%\">2.5<\/span><span class=\"tick num\" style=\"left:100%\">3%<\/span><\/div><\/div>\n  <ul class=\"pins-list\" aria-hidden=\"true\"><li><strong class=\"num\">0.5%<\/strong><span>L\u00edmite en lociones corporales<a class=\"ref\" href=\"#src-2\">2<\/a><\/span><\/li><li><strong class=\"num\">2%<\/strong><span>L\u00edmite en cremas faciales<a class=\"ref\" href=\"#src-2\">2<\/a><\/span><\/li><\/ul><\/div><\/div><\/section>\n<section class=\"sec products\" id=\"produits\" aria-labelledby=\"h-p\"><div class=\"wrap\">\n  <div class=\"p-head\"><div><h2 class=\"h2\" id=\"h-p\">\u00bfQu\u00e9 productos contienen alfa-arbutina?<\/h2>\n  <p class=\"lede\">Nuestro <a class=\"txt-link\" href=\"https:\/\/carmelcosmeticslabs.com\/es\/catalogo-cosmetica-marca-blanca\/\">cat\u00e1logo de marca blanca<\/a> incluye 2 f\u00f3rmulas con alfa-arbutina: es el activo principal en 2 de ellas y un ingrediente complementario en las dem\u00e1s. Todas las categor\u00edas se pueden personalizar (f\u00f3rmula, fragancia, envase).<\/p><\/div>\n  <\/div>\n  <div class=\"p-cols\" style=\"--pc:1\"><div class=\"p-col on\" id=\"pc-visage\" role=\"tabpanel\"><h3><span class=\"count num\">2<\/span>Rostro<\/h3><p>Activo principal, junto con el \u00e1cido k\u00f3jico, del s\u00e9rum y de la crema antimanchas del cat\u00e1logo.<\/p><ul><li><a href=\"https:\/\/carmelcosmeticslabs.com\/es\/catalogo-cosmetica-marca-blanca\/cremas-faciales-marca-blanca\/\"><span>Cremas faciales<\/span><span class=\"n\">1<\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><li><a href=\"https:\/\/carmelcosmeticslabs.com\/es\/catalogo-cosmetica-marca-blanca\/serums-faciales-marca-blanca\/\"><span>S\u00e9rums faciales<\/span><span class=\"n\">1<\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><\/ul><div class=feat><a href=\"https:\/\/carmelcosmeticslabs.com\/es\/catalogo-cosmetica-marca-blanca\/serums-faciales-marca-blanca\/serum-antimanchas-acido-kojico-marca-blanca\/\"><span>S\u00e9rum antimanchas con \u00e1cido k\u00f3jico<small>Activo principal<\/small><\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><a href=\"https:\/\/carmelcosmeticslabs.com\/es\/catalogo-cosmetica-marca-blanca\/cremas-faciales-marca-blanca\/crema-antimanchas-acido-kojico-marca-blanca\/\"><span>Crema antimanchas con \u00e1cido k\u00f3jico<small>Activo principal<\/small><\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/div><\/div><\/div>\n  <div class=\"pairs\"><p>En nuestras f\u00f3rmulas, se combina con mayor frecuencia con<\/p><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/es\/glosario-ingredientes-cosmeticos\/extracto-de-regaliz\/\">Extracto de regaliz <span class=\"num\">2<\/span><\/a><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/es\/glosario-ingredientes-cosmeticos\/niacinamida\/\">Niacinamida <span class=\"num\">2<\/span><\/a><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/es\/glosario-ingredientes-cosmeticos\/pantenol\/\">Pantenol <span class=\"num\">2<\/span><\/a><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/es\/glosario-ingredientes-cosmeticos\/vitamina-c\/\">Vitamina C <span class=\"num\">2<\/span><\/a><\/div>\n  <\/div><\/section>\n<section class=\"sec\" id=\"comparatif\" aria-labelledby=\"h-cmp\"><div class=\"wrap\">\n  <h2 class=\"h2\" id=\"h-cmp\">\u00bfAlfa-arbutina, arbutina, \u00e1cido k\u00f3jico o niacinamida?<\/h2><p class=\"lede\">Cuatro activos que suelen compararse para unificar el tono. No son excluyentes: nuestro s\u00e9rum y nuestra crema antimanchas combinan alfa-arbutina, \u00e1cido k\u00f3jico y niacinamida.<\/p>\n  <div class=\"seg c-pick\" role=\"group\" aria-label=\"Comparar con\" id=\"cpick\"><button type=\"button\" aria-pressed=\"true\" data-c=\"3\">Arbutina<\/button><button type=\"button\" aria-pressed=\"false\" data-c=\"4\">\u00c1cido k\u00f3jico<\/button><button type=\"button\" aria-pressed=\"false\" data-c=\"5\">Niacinamida<\/button><\/div>\n  <div class=\"tbl-wrap\"><table class=\"cmp\" id=\"cmp\" data-c=\"3\"><colgroup><col><col class=\"me\"><col><col><col><\/colgroup>\n  <thead><tr><td><\/td><th scope=\"col\">Alfa-arbutina<\/th><th scope=\"col\">Arbutina (beta)<\/th><th scope=\"col\">\u00c1cido k\u00f3jico<\/th><th scope=\"col\">Niacinamida<\/th><\/tr><\/thead><tbody><tr><th scope=\"row\">Origen<\/th><td>S\u00edntesis enzim\u00e1tica<a class=\"ref\" href=\"#src-3\">3<\/a><\/td><td>Presente en numerosas plantas<a class=\"ref\" href=\"#src-3\">3<\/a><\/td><td>No se aborda aqu\u00ed<\/td><td>Vitamina B3<\/td><\/tr><tr><th scope=\"row\">Normativa de la UE<\/th><td>Restringida: 2% en cremas faciales, 0.5% en lociones corporales<a class=\"ref\" href=\"#src-2\">2<\/a><\/td><td>Restringida: 7% en cremas faciales<a class=\"ref\" href=\"#src-2\">2<\/a><\/td><td>Restringido: 1% para rostro y manos<a class=\"ref\" href=\"#src-2\">2<\/a><\/td><td>Sin restricciones<\/td><\/tr><tr><th scope=\"row\">Tirosinasa humana<\/th><td>Inhibici\u00f3n m\u00e1s intensa que la forma beta<a class=\"ref\" href=\"#src-5\">5<\/a><\/td><td>Inhibici\u00f3n menos intensa que la forma alfa<a class=\"ref\" href=\"#src-5\">5<\/a><\/td><td>No se compara en estos estudios<\/td><td>Otro mecanismo de acci\u00f3n: consulte la ficha de la niacinamida<\/td><\/tr><tr><th scope=\"row\">Aspecto que vigilar<\/th><td>Hidroquinona al nivel de trazas inevitables<a class=\"ref\" href=\"#src-3\">3<\/a><\/td><td>Libera hidroquinona a pH de 3 o inferior<a class=\"ref\" href=\"#src-3\">3<\/a><\/td><td>L\u00edmite de concentraci\u00f3n en el anexo III<a class=\"ref\" href=\"#src-2\">2<\/a><\/td><td>Consulte la ficha de la niacinamida<\/td><\/tr><\/tbody><\/table><\/div><\/div><\/section>\n<section class=\"sec\" id=\"faq\" aria-labelledby=\"h-faq\"><div class=\"wrap faq-grid\">\n  <h2 class=\"h2\" id=\"h-faq\">Preguntas frecuentes sobre alfa-arbutina<\/h2><div class=\"faq\"><details open><summary>\u00bfQu\u00e9 es la alfa-arbutina?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">Es un gluc\u00f3sido de la hidroquinona, el 4-hidroxifenil-alfa-D-glucopiran\u00f3sido (CAS 84380-01-8). CosIng le atribuye funciones antioxidantes, aclaradoras y acondicionadoras de la piel<a class=\"ref\" href=\"#src-1\">1<\/a>. Se obtiene por s\u00edntesis enzim\u00e1tica, mientras que la beta-arbutina est\u00e1 presente en numerosas plantas<a class=\"ref\" href=\"#src-3\">3<\/a>.<\/div><\/details><details><summary>\u00bfQu\u00e9 beneficios tiene la alfa-arbutina?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">En el laboratorio, reduce la formaci\u00f3n de melanina en c\u00e9lulas y en un modelo de piel humana<a class=\"ref\" href=\"#src-4\">4<\/a> e inhibe la tirosinasa humana con m\u00e1s intensidad que la beta-arbutina<a class=\"ref\" href=\"#src-5\">5<\/a>. Los ensayos cl\u00ednicos en piel sin alteraciones son escasos: una revisi\u00f3n de 2021 pide ensayos de mayor calidad<a class=\"ref\" href=\"#src-8\">8<\/a>.<\/div><\/details><details><summary>\u00bfQu\u00e9 porcentaje de alfa-arbutina se permite en cosm\u00e9tica?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">El Reglamento (UE) 2024\/996 fija un m\u00e1ximo del 2% en cremas faciales y del 0.5% en lociones corporales, a partir del dictamen del SCCS<a class=\"ref\" href=\"#src-2\">2<\/a><a class=\"ref\" href=\"#src-3\">3<\/a>. El nivel de hidroquinona debe ser lo m\u00e1s bajo posible y nunca superar el de trazas inevitables<a class=\"ref\" href=\"#src-2\">2<\/a>.<\/div><\/details><details><summary>\u00bfSe puede combinar alfa-arbutina con vitamina C, \u00e1cido k\u00f3jico y niacinamida?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">S\u00ed, son combinaciones habituales. Nuestra crema y nuestro s\u00e9rum antimanchas combinan \u00e1cido k\u00f3jico y alfa-arbutina, con niacinamida y vitamina C entre sus activos complementarios. El \u00e1cido k\u00f3jico tiene su propio l\u00edmite del 1% para productos de rostro y manos<a class=\"ref\" href=\"#src-2\">2<\/a>. La estabilidad de la f\u00f3rmula final se comprueba mediante ensayos de laboratorio.<\/div><\/details><details><summary>\u00bfAlfa-arbutina por la ma\u00f1ana o por la noche?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">Ninguna de las fuentes citadas establece un momento de aplicaci\u00f3n.<\/div><\/details><details><summary>\u00bfEs segura la alfa-arbutina? \u00bfTiene efectos secundarios?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">El SCCS la considera segura al 2% en cremas faciales y al 0.5% en lociones corporales, utilizadas por separado o conjuntamente<a class=\"ref\" href=\"#src-3\">3<\/a>. El aspecto que debe vigilarse es la hidroquinona, que debe mantenerse al nivel de trazas inevitables<a class=\"ref\" href=\"#src-2\">2<\/a>. La absorci\u00f3n cut\u00e1nea medida in vitro en piel humana es baja<a class=\"ref\" href=\"#src-3\">3<\/a>.<\/div><\/details><details><summary>\u00bfSe puede utilizar alfa-arbutina durante el embarazo?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">Las fuentes citadas no abordan el embarazo. Como con cualquier cuidado espec\u00edfico, conviene consultar a un profesional sanitario.<\/div><\/details><details><summary>\u00bfPueden fabricar un s\u00e9rum con alfa-arbutina para mi marca?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">S\u00ed. Nuestro laboratorio <a class=\"txt-link\" href=\"https:\/\/carmelcosmeticslabs.com\/es\/certificaciones-iso-22716\/\">certificado ISO 22716<\/a> ofrece 2 f\u00f3rmulas con alfa-arbutina del cat\u00e1logo (s\u00e9rum y crema antimanchas) que puede personalizar, o una <a class=\"txt-link\" href=\"https:\/\/carmelcosmeticslabs.com\/es\/laboratorio-formulacion-cosmetica\/\">f\u00f3rmula a medida<\/a>. Las muestras son gratuitas.<\/div><\/details><\/div><\/div><\/section>\n<section class=\"sec\" id=\"plus\" aria-labelledby=\"h-more\" style=\"padding-top:0\"><div class=\"wrap more-grid\">\n  <div><h2 class=\"h2\" id=\"h-more\">Lecturas complementarias<\/h2><div class=\"hubs\"><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/es\/glosario-ingredientes-cosmeticos\/\">Glosario de ingredientes<\/a><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/es\/catalogo-cosmetica-marca-blanca\/serums-faciales-marca-blanca\/\">S\u00e9rums faciales en marca blanca<\/a><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/es\/fabricacion-cosmetica-terceros-guia-completa-fabricar-sus-productos\/\">Gu\u00eda de fabricaci\u00f3n de cosm\u00e9ticos por encargo<\/a><\/div><\/div>\n  <ul class=\"more-list\"><li><a href=\"https:\/\/carmelcosmeticslabs.com\/es\/top-10-ingredientes-cosmeticos-tendencia-2026-activos-debe\/\"><span><strong>Los 10 ingredientes cosm\u00e9ticos de tendencia en 2026<\/strong><small>Incluye la alfa-arbutina entre las combinaciones de un activo de tendencia<\/small><\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><li><a href=\"https:\/\/carmelcosmeticslabs.com\/es\/reglamento-cosmetico-europeo-responder-nuevas-normativas-expectativas-consumidor\/\"><span><strong>Normativa cosm\u00e9tica de la UE: nuevas normas y expectativas del consumidor de gama alta<\/strong><small>El marco europeo aplicable a los activos restringidos<\/small><\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><\/ul><\/div><\/section>\n<section class=\"sec sources\" id=\"sources\" aria-labelledby=\"h-s\"><div class=\"wrap\">\n  <h2 class=\"h2\" id=\"h-s\">Fuentes<\/h2><p class=\"lede\">Estudios revisados por pares y fuentes normativas oficiales, consultados el 2 de noviembre de 2026.<\/p>\n  <ol class=\"src\"><li id=\"src-1\"><span>Comisi\u00f3n Europea. <em>CosIng, ficha ALPHA-ARBUTIN<\/em> (CAS 84380-01-8, CE 617-561-8). <a class=\"txt-link\" href=\"https:\/\/ec.europa.eu\/growth\/tools-databases\/cosing\/details\/54359\" target=\"_blank\" rel=\"noopener\">ec.europa.eu\/growth\/tools-databases\/cosing<\/a><\/span><\/li><li id=\"src-2\"><span>Reglamento (UE) 2024\/996 de la Comisi\u00f3n, de 3 de abril de 2024, por el que se modifica el Reglamento (CE) n.\u00ba 1223\/2009 (vitamina A, alfa-arbutina, arbutina y otras sustancias): anexo III, entradas 375 (\u00e1cido k\u00f3jico), 377 (alfa-arbutina) y 378 (arbutina). <a class=\"txt-link\" href=\"https:\/\/eur-lex.europa.eu\/eli\/reg\/2024\/996\/oj\" target=\"_blank\" rel=\"noopener\">eur-lex.europa.eu<\/a><\/span><\/li><li id=\"src-3\"><span>Comit\u00e9 Cient\u00edfico de Seguridad de los Consumidores (SCCS). <em>Opinion on the safety of alpha-arbutin and beta-arbutin in cosmetic products<\/em>, SCCS\/1642\/22, versi\u00f3n final de 31 de enero de 2023. <a class=\"txt-link\" href=\"https:\/\/health.ec.europa.eu\/publications\/safety-alpha-arbutin-and-beta-arbutin-cosmetic-products_en\" target=\"_blank\" rel=\"noopener\">health.ec.europa.eu<\/a><\/span><\/li><li id=\"src-4\"><span>Sugimoto K, Nishimura T, Nomura K, Sugimoto K, Kuriki T. <em>Inhibitory effects of alpha-arbutin on melanin synthesis in cultured human melanoma cells and a three-dimensional human skin model.<\/em> Biol Pharm Bull. 2004;27(4):510-514. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1248\/bpb.27.510\" target=\"_blank\" rel=\"noopener\">doi:10.1248\/bpb.27.510<\/a><span class=\"tag\">Ezaki Glico (fabricante de alfa-arbutina)<\/span><\/span><\/li><li id=\"src-5\"><span>Sugimoto K, Nishimura T, Nomura K, Sugimoto K, Kuriki T. <em>Syntheses of arbutin-alpha-glycosides and a comparison of their inhibitory effects with those of alpha-arbutin and arbutin on human tyrosinase.<\/em> Chem Pharm Bull (Tokyo). 2003;51(7):798-801. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1248\/cpb.51.798\" target=\"_blank\" rel=\"noopener\">doi:10.1248\/cpb.51.798<\/a><span class=\"tag\">Ezaki Glico (fabricante de alfa-arbutina)<\/span><\/span><\/li><li id=\"src-6\"><span>Funayama M, Arakawa H, Yamamoto R, et al. <em>Effects of alpha- and beta-arbutin on activity of tyrosinases from mushroom and mouse melanoma.<\/em> Biosci Biotechnol Biochem. 1995;59(1):143-144. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1271\/bbb.59.143\" target=\"_blank\" rel=\"noopener\">doi:10.1271\/bbb.59.143<\/a><span class=\"tag\">Kurabo Industries<\/span><\/span><\/li><li id=\"src-7\"><span>Khan HMS, Tanveer N, Arshad T, et al. <em>Encapsulation of alpha arbutin, a depigmenting agent, in nanosized ethosomes: in vitro and in vivo human studies.<\/em> Heliyon. 2023;9(9):e19326. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1016\/j.heliyon.2023.e19326\" target=\"_blank\" rel=\"noopener\">doi:10.1016\/j.heliyon.2023.e19326<\/a><\/span><\/li><li id=\"src-8\"><span>Saeedi M, Khezri K, Seyed Zakaryaei A, Mohammadamini H. <em>A comprehensive review of the therapeutic potential of \u03b1-arbutin.<\/em> Phytother Res. 2021;35(8):4136-4154. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1002\/ptr.7076\" target=\"_blank\" rel=\"noopener\">doi:10.1002\/ptr.7076<\/a><\/span><\/li><li id=\"src-9\"><span>Desmedt B, Courselle P, De Beer JO, et al. <em>Overview of skin whitening agents with an insight into the illegal cosmetic market in Europe.<\/em> J Eur Acad Dermatol Venereol. 2016;30(6):943-950. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1111\/jdv.13595\" target=\"_blank\" rel=\"noopener\">doi:10.1111\/jdv.13595<\/a><\/span><\/li><\/ol><\/div><\/section>\n\n<div class=\"fab\" id=\"fab\"><a class=\"btn\" href=\"#consultation\">Crear un producto con alfa-arbutina <span class=\"knob\" aria-hidden=\"true\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.8\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/span><\/a><\/div><div class=\"scrim\" id=\"scrim\"><\/div><div class=\"pop\" id=\"pop\" role=\"dialog\" aria-modal=\"false\" aria-labelledby=\"pop-n\" hidden><div class=\"pop-n\" id=\"pop-n\"><\/div><div class=\"pop-body\" id=\"pop-body\"><\/div><div class=\"pop-foot\"><a class=\"txt-link\" id=\"pop-all\" href=\"#sources\">Todas las fuentes<\/a><button class=\"pop-x\" type=\"button\" id=\"pop-x\">Cerrar<\/button><\/div><\/div>\n<\/div>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@graph\": [{\"@type\": \"WebPage\", \"@id\": \"https:\/\/carmelcosmeticslabs.com\/es\/glosario-ingredientes-cosmeticos\/alfa-arbutina\/#webpage\", \"url\": 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CosIng le atribuye funciones antioxidantes, aclaradoras y acondicionadoras de la piel. Se obtiene por s\u00edntesis enzim\u00e1tica, mientras que la beta-arbutina est\u00e1 presente en numerosas plantas.\"}}, {\"@type\": \"Question\", \"name\": \"\u00bfQu\u00e9 beneficios tiene la alfa-arbutina?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"En el laboratorio, reduce la formaci\u00f3n de melanina en c\u00e9lulas y en un modelo de piel humana e inhibe la tirosinasa humana con m\u00e1s intensidad que la beta-arbutina. Los ensayos cl\u00ednicos en piel sin alteraciones son escasos: una revisi\u00f3n de 2021 pide ensayos de mayor calidad.\"}}, {\"@type\": \"Question\", \"name\": \"\u00bfQu\u00e9 porcentaje de alfa-arbutina se permite en cosm\u00e9tica?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"El Reglamento (UE) 2024\/996 fija un m\u00e1ximo del 2% en cremas faciales y del 0.5% en lociones corporales, a partir del dictamen del SCCS. El nivel de hidroquinona debe ser lo m\u00e1s bajo posible y nunca superar el de trazas inevitables.\"}}, {\"@type\": \"Question\", \"name\": \"\u00bfSe puede combinar alfa-arbutina con vitamina C, \u00e1cido k\u00f3jico y niacinamida?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"S\u00ed, son combinaciones habituales. Nuestra crema y nuestro s\u00e9rum antimanchas combinan \u00e1cido k\u00f3jico y alfa-arbutina, con niacinamida y vitamina C entre sus activos complementarios. El \u00e1cido k\u00f3jico tiene su propio l\u00edmite del 1% para productos de rostro y manos. 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var(--line)!important;border-radius:14px!important;padding:13px 15px!important;height:auto!important;min-height:50px;box-shadow:none!important;transition:border-color .2s ease,box-shadow .2s ease,background-color .2s ease}\nbody .lpf-card .iti input[type=tel]{padding-left:52px!important}\nbody .lpf-card textarea{min-height:120px;resize:vertical}\nbody .lpf-card input:focus,body .lpf-card select:focus,body .lpf-card textarea:focus{outline:0!important;border-color:var(--teal)!important;background-color:var(--paper)!important;box-shadow:0 0 0 4px rgb(47 114 102\/.14)!important}\nbody .lpf-card ::placeholder{color:#8aa09d;opacity:1}\nbody .lpf-card .wpforms-submit-container{margin-top:6px!important;padding:0!important}\nbody .lpf-card button.wpforms-submit{width:100%!important;display:inline-flex!important;align-items:center;justify-content:center;gap:10px;font:650 16px\/1 var(--f-body)!important;color:#fff!important;background:var(--deep)!important;border:0!important;border-radius:99px!important;padding:19px 26px!important;min-height:58px;cursor:pointer;box-shadow:0 14px 30px -14px rgb(16 58 53\/.7)!important;transition:transform .16s cubic-bezier(.23,1,.32,1),background-color .2s ease}\n@media (hover:hover) and (pointer:fine){body .lpf-card button.wpforms-submit:hover{background:var(--teal)!important}}\nbody .lpf-card button.wpforms-submit:active{transform:scale(.98)}\nbody .lpf-card .wpforms-error,body .lpf-card label.wpforms-error,body .lpf-card em.wpforms-error{display:block;color:#b3261e!important;font-size:12.5px!important;margin-top:5px!important}\nbody .lpf-card input.wpforms-error,body .lpf-card select.wpforms-error,body .lpf-card textarea.wpforms-error{border-color:#d26a5f!important}\nbody .lpf-card .wpforms-confirmation-container-full{background:var(--mint)!important;border:0!important;border-radius:18px!important;color:var(--ink)!important;padding:22px!important}\n@media (max-width:520px){body .lpf-card .wpforms-field-name .wpforms-field-row{grid-template-columns:1fr}}\n<\/style><div class=\"dv-card-head\"><img loading=\"lazy\" class=\"dv-avatar\" src=\"https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/09\/lancer-marque-cosmetique-etape-1-expert-carmel-768x953.webp\" alt=\"Especialista de producto de Carmel Cosmetics Labs con una fundadora de marca\" width=\"768\" height=\"953\" loading=\"lazy\" decoding=\"async\" title=\"| Carmel Cosmetics Labs\"><div><h2>Cu\u00e9ntenos su proyecto<\/h2><p>Un especialista de producto estudia su solicitud y le responde por el canal que prefiera.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-320737f dv-form eael-wpforms-labels-yes eael-wpforms-form-button-custom elementor-widget elementor-widget-eael-wpforms\" data-id=\"320737f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-wpforms.default\">\n\t\t\t\t\t            <div class=\"eael-contact-form eael-wpforms eael-wpforms-align-default\">\n                                <div class=\"wpforms-container wpforms-container-full wpforms-render-modern\" id=\"wpforms-51144\"><form id=\"wpforms-form-51144\" class=\"wpforms-validate wpforms-form wpforms-ajax-form\" data-formid=\"51144\" method=\"post\" enctype=\"multipart\/form-data\" action=\"\/es\/wp-json\/wp\/v2\/pages\/57065\" data-token=\"8f94df23b1ccab2c62dd3b47ec22c230\" data-token-time=\"1794233084\"><div class=\"wpforms-head-container\"><div class=\"wpforms-title\">Lead ES \u2013 Demande de devis<\/div><\/div><noscript class=\"wpforms-error-noscript\">Por favor, activa JavaScript en tu navegador para completar este formulario.<\/noscript><div id=\"wpforms-error-noscript\" style=\"display: none;\">Por favor, activa JavaScript en tu navegador para completar este formulario.<\/div><div class=\"wpforms-field-container\"><div id=\"wpforms-51144-field_0-container\" class=\"wpforms-field wpforms-field-name\" data-field-type=\"name\" data-field-id=\"0\"><fieldset><legend class=\"wpforms-field-label wpforms-label-hide\" aria-hidden=\"false\">Nombre <span class=\"wpforms-required-label\" aria-hidden=\"true\">*<\/span><\/legend><div class=\"wpforms-field-row wpforms-field-large\"><div class=\"wpforms-field-row-block wpforms-first wpforms-one-half\"><input type=\"text\" id=\"wpforms-51144-field_0\" class=\"wpforms-field-name-first wpforms-field-required\" name=\"wpforms[fields][0][first]\" placeholder=\"Nombre\" aria-errormessage=\"wpforms-51144-field_0-error\" required><label for=\"wpforms-51144-field_0\" class=\"wpforms-field-sublabel after wpforms-sublabel-hide\">Pr\u00e9nom<\/label><\/div><div class=\"wpforms-field-row-block wpforms-one-half\"><input type=\"text\" id=\"wpforms-51144-field_0-last\" class=\"wpforms-field-name-last wpforms-field-required\" name=\"wpforms[fields][0][last]\" placeholder=\"Apellidos\" aria-errormessage=\"wpforms-51144-field_0-last-error\" required><label for=\"wpforms-51144-field_0-last\" class=\"wpforms-field-sublabel after wpforms-sublabel-hide\">Nom<\/label><\/div><\/div><\/fieldset><\/div><div id=\"wpforms-51144-field_1-container\" class=\"wpforms-field wpforms-field-email\" data-field-type=\"email\" data-field-id=\"1\"><label class=\"wpforms-field-label wpforms-label-hide\" for=\"wpforms-51144-field_1\" aria-hidden=\"false\">Correo electr\u00f3nico <span class=\"wpforms-required-label\" aria-hidden=\"true\">*<\/span><\/label><input type=\"email\" id=\"wpforms-51144-field_1\" class=\"wpforms-field-large wpforms-field-required\" name=\"wpforms[fields][1]\" placeholder=\"Su correo electr\u00f3nico\" spellcheck=\"false\" aria-errormessage=\"wpforms-51144-field_1-error\" required><\/div><div id=\"wpforms-51144-field_3-container\" class=\"wpforms-field wpforms-field-phone\" data-field-type=\"phone\" data-field-id=\"3\"><label class=\"wpforms-field-label wpforms-label-hide\" for=\"wpforms-51144-field_3\" aria-hidden=\"false\">Tel\u00e9fono <span class=\"wpforms-required-label\" aria-hidden=\"true\">*<\/span><\/label><input type=\"tel\" id=\"wpforms-51144-field_3\" class=\"wpforms-field-large wpforms-field-required wpforms-smart-phone-field\" data-rule-smart-phone-field=\"true\" name=\"wpforms[fields][3]\" placeholder=\"Su tel\u00e9fono\" aria-label=\"Tel\u00e9fono\" aria-errormessage=\"wpforms-51144-field_3-error\" required><\/div><div id=\"wpforms-51144-field_4-container\" class=\"wpforms-field wpforms-field-select wpforms-field-select-style-modern\" data-field-type=\"select\" data-field-id=\"4\"><label class=\"wpforms-field-label\" for=\"wpforms-51144-field_4\">Medio de contacto preferido <span class=\"wpforms-required-label\" aria-hidden=\"true\">*<\/span><\/label><select id=\"wpforms-51144-field_4\" class=\"wpforms-field-large wpforms-field-required choicesjs-select\" data-size-class=\"wpforms-field-row wpforms-field-large\" data-search-enabled=\"\" name=\"wpforms[fields][4]\" required=\"required\"><option value=\"\" class=\"placeholder\" disabled  selected='selected'>Elija su medio de contacto preferido<\/option><option value=\"WhatsApp\"  class=\"choice-1 depth-1\"  >WhatsApp<\/option><option value=\"Correo electr\u00f3nico\"  class=\"choice-2 depth-1\"  >Correo electr\u00f3nico<\/option><option value=\"Llamada telef\u00f3nica\"  class=\"choice-3 depth-1\"  >Llamada telef\u00f3nica<\/option><\/select><\/div><div id=\"wpforms-51144-field_2-container\" class=\"wpforms-field wpforms-field-textarea\" data-field-type=\"textarea\" data-field-id=\"2\"><label class=\"wpforms-field-label\" for=\"wpforms-51144-field_2\">Describa brevemente su proyecto: <span class=\"wpforms-required-label\" aria-hidden=\"true\">*<\/span><\/label><textarea id=\"wpforms-51144-field_2\" class=\"wpforms-field-medium wpforms-field-required\" name=\"wpforms[fields][2]\" placeholder=\"Contexto del proyecto, tipo de productos, fecha de lanzamiento prevista, mercado(s) objetivo, etc.\" aria-errormessage=\"wpforms-51144-field_2-error\" required><\/textarea><\/div><div id=\"wpforms-51144-field_5-container\" class=\"wpforms-field wpforms-field-hidden ccl-utm_source\" data-field-type=\"hidden\" data-field-id=\"5\"><input type=\"hidden\" id=\"wpforms-51144-field_5\" name=\"wpforms[fields][5]\"><\/div><div id=\"wpforms-51144-field_6-container\" class=\"wpforms-field wpforms-field-hidden ccl-utm_medium\" data-field-type=\"hidden\" data-field-id=\"6\"><input type=\"hidden\" id=\"wpforms-51144-field_6\" name=\"wpforms[fields][6]\"><\/div><div id=\"wpforms-51144-field_7-container\" class=\"wpforms-field wpforms-field-hidden ccl-utm_campaign\" data-field-type=\"hidden\" data-field-id=\"7\"><input type=\"hidden\" id=\"wpforms-51144-field_7\" name=\"wpforms[fields][7]\"><\/div><div 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class=\"wpforms-field wpforms-field-hidden ccl-wbraid\" data-field-type=\"hidden\" data-field-id=\"12\"><input type=\"hidden\" id=\"wpforms-51144-field_12\" name=\"wpforms[fields][12]\"><\/div><div id=\"wpforms-51144-field_13-container\" class=\"wpforms-field wpforms-field-hidden ccl-fbclid\" data-field-type=\"hidden\" data-field-id=\"13\"><input type=\"hidden\" id=\"wpforms-51144-field_13\" name=\"wpforms[fields][13]\"><\/div><div id=\"wpforms-51144-field_14-container\" class=\"wpforms-field wpforms-field-hidden ccl-landing\" data-field-type=\"hidden\" data-field-id=\"14\"><input type=\"hidden\" id=\"wpforms-51144-field_14\" name=\"wpforms[fields][14]\"><\/div><div id=\"wpforms-51144-field_15-container\" class=\"wpforms-field wpforms-field-hidden ccl-referrer\" data-field-type=\"hidden\" data-field-id=\"15\"><input type=\"hidden\" id=\"wpforms-51144-field_15\" name=\"wpforms[fields][15]\"><\/div><div id=\"wpforms-51144-field_16-container\" class=\"wpforms-field wpforms-field-hidden ccl-first_touch\" data-field-type=\"hidden\" data-field-id=\"16\"><input type=\"hidden\" id=\"wpforms-51144-field_16\" name=\"wpforms[fields][16]\"><\/div><div id=\"wpforms-51144-field_17-container\" class=\"wpforms-field wpforms-field-hidden ccl-canal\" data-field-type=\"hidden\" data-field-id=\"17\"><input type=\"hidden\" id=\"wpforms-51144-field_17\" name=\"wpforms[fields][17]\"><\/div><div id=\"wpforms-51144-field_18-container\" class=\"wpforms-field wpforms-field-hidden ccl-campagne\" data-field-type=\"hidden\" data-field-id=\"18\"><input type=\"hidden\" id=\"wpforms-51144-field_18\" name=\"wpforms[fields][18]\"><\/div><\/div><!-- .wpforms-field-container --><div class=\"wpforms-submit-container\" ><input type=\"hidden\" name=\"wpforms[id]\" value=\"51144\"><input type=\"hidden\" name=\"wpforms[time_token]\" value=\"1794233084.b3ae5c1ad7aa8db6efe707dbb4e0de5c9dafb47971abe8aeea0094288970bc39\"><input type=\"hidden\" name=\"page_title\" value=\"\"><input type=\"hidden\" name=\"page_url\" value=\"https:\/\/carmelcosmeticslabs.com\/es\/wp-json\/wp\/v2\/pages\/57065\"><input type=\"hidden\" name=\"url_referer\" value=\"\"><button type=\"submit\" name=\"wpforms[submit]\" id=\"wpforms-submit-51144\" class=\"wpforms-submit\" data-alt-text=\"Enviando\u2026\" data-submit-text=\"Consulta gratuita\" aria-live=\"assertive\" value=\"wpforms-submit\">Consulta gratuita<\/button><img decoding=\"async\" src=\"https:\/\/carmelcosmeticslabs.com\/wp-content\/plugins\/wpforms\/assets\/images\/submit-spin.svg\" class=\"wpforms-submit-spinner\" style=\"display: none;\" width=\"26\" height=\"26\" alt=\"Cargando\" title=\"| Carmel Cosmetics Labs\"><\/div><\/form><\/div>  <!-- .wpforms-container -->            <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c9018c elementor-widget elementor-widget-html\" data-id=\"3c9018c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<p class=\"dv-reassure\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><rect x=\"4\" y=\"11\" width=\"16\" height=\"10\" rx=\"2\"\/><path d=\"M8 11V7a4 4 0 0 1 8 0v4\"\/><\/svg>Sin compromiso. Su informaci\u00f3n es confidencial y solo se utiliza para preparar su presupuesto.<\/p><script>(function(){var s=document.getElementById('consultation');if(!s)return;\nvar re=\/\\\/(demande-de-devis|request-a-quote|kostenvoranschlag-anfordern|%d8%b7%d9%84%d8%a8-%d8%a7%d9%82%d8%aa%d8%a8%d8%a7%d8%b3|\u0637\u0644\u0628-\u0627\u0642\u062a\u0628\u0627\u0633)\\\/?([?#].*)?$\/i;\nvar root=s.closest('[data-elementor-type=\"wp-page\"]')||document;\nroot.querySelectorAll('a[href]').forEach(function(a){var h=a.getAttribute('href')||'',d=h;try{d=decodeURIComponent(h);}catch(e){}if(re.test(h)||re.test(d)){a.setAttribute('href','#consultation');}});\ndocument.addEventListener('click',function(e){var a=e.target.closest&&e.target.closest('a[href=\"#consultation\"]');if(!a)return;e.preventDefault();\nvar sm=!matchMedia('(prefers-reduced-motion: reduce)').matches;s.scrollIntoView({behavior:sm?'smooth':'auto',block:'start'});\nvar f=s.querySelector('form input:not([type=hidden]),form select,form textarea');\nvar off=function(){return Math.abs(s.getBoundingClientRect().top-110)>24},fix=function(){if(off())s.scrollIntoView({behavior:'auto',block:'start'});setTimeout(function(){if(off())s.scrollIntoView({behavior:'auto',block:'start'});if(f)try{f.focus({preventScroll:true})}catch(_){}},350)};\nvar last=-1,still=0,n=0,iv=setInterval(function(){var y=scrollY;still=(y===last)?still+1:0;last=y;if(still>=3||++n>50){clearInterval(iv);fix();}},120);\nif(history.replaceState)history.replaceState(null,'','#consultation');});})();<\/script>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Alfa-arbutina en cosm\u00e9tica: INCI, CAS, estudios de laboratorio, l\u00edmites del Reglamento (UE) 2024\/996 (2% facial) y 2 f\u00f3rmulas de marca blanca.<\/p>\n","protected":false},"author":3,"featured_media":54192,"parent":20322,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-57065","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/carmelcosmeticslabs.com\/es\/wp-json\/wp\/v2\/pages\/57065","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carmelcosmeticslabs.com\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/carmelcosmeticslabs.com\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/carmelcosmeticslabs.com\/es\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/carmelcosmeticslabs.com\/es\/wp-json\/wp\/v2\/comments?post=57065"}],"version-history":[{"count":1,"href":"https:\/\/carmelcosmeticslabs.com\/es\/wp-json\/wp\/v2\/pages\/57065\/revisions"}],"predecessor-version":[{"id":58189,"href":"https:\/\/carmelcosmeticslabs.com\/es\/wp-json\/wp\/v2\/pages\/57065\/revisions\/58189"}],"up":[{"embeddable":true,"href":"https:\/\/carmelcosmeticslabs.com\/es\/wp-json\/wp\/v2\/pages\/20322"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/carmelcosmeticslabs.com\/es\/wp-json\/wp\/v2\/media\/54192"}],"wp:attachment":[{"href":"https:\/\/carmelcosmeticslabs.com\/es\/wp-json\/wp\/v2\/media?parent=57065"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}