{"id":55611,"date":"2026-11-03T10:53:46","date_gmt":"2026-11-03T10:53:46","guid":{"rendered":"https:\/\/carmelcosmeticslabs.com\/?page_id=55611"},"modified":"2026-11-05T12:33:11","modified_gmt":"2026-11-05T12:33:11","slug":"betaine","status":"publish","type":"page","link":"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/betaine\/","title":{"rendered":"Betaine"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"55611\" class=\"elementor elementor-55611 elementor-55509 elementor-bc-flex-widget\" data-elementor-post-type=\"page\">\n\t\t\t\t<div data-particle_enable=\"false\" data-particle-mobile-disabled=\"false\" class=\"elementor-element elementor-element-3befd94 e-flex e-con-full e-con e-parent\" data-id=\"3befd94\" data-element_type=\"container\" data-e-type=\"container\" id=\"ing-betaine\">\n\t\t\t\t<div class=\"elementor-element elementor-element-14ce2c3 elementor-widget elementor-widget-html\" data-id=\"14ce2c3\" 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.pins-list{display:block}.ig .track .pin{display:none}}\n<\/style>\n<div class=\"ig\" data-ing=\"betaine\" lang=\"en\" data-copy=\"Copy\" data-copied=\"Copied\">\n<nav class=\"crumbs wrap\" aria-label=\"Breadcrumb\"><ol>\n  <li><a href=\"https:\/\/carmelcosmeticslabs.com\/en\/\">Home<\/a><\/li><li><a href=\"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/\">Ingredient glossary<\/a><\/li><li aria-current=\"page\">Betaine<\/li><\/ol><\/nav>\n<header class=\"wrap hero\" id=\"top\">\n  <div class=\"hero-copy\">\n    <h1 class=\"h1-long\">Betaine (trimethylglycine)<\/h1>\n    <p class=\"brief\">Betaine, or trimethylglycine, is a water-soluble organic osmolyte that skin is able to transport<a class=\"ref\" href=\"#src-2\">2<\/a>. Its CosIng function is humectant<a class=\"ref\" href=\"#src-1\">1<\/a>. Cosmetic data come mostly from the laboratory: it acts on barrier proteins in human skin culture<a class=\"ref\" href=\"#src-2\">2<\/a>. No clinical trial isolates it yet. It is not the same as cocamidopropyl betaine, a surfactant<a class=\"ref\" href=\"#src-9\">9<\/a>.<\/p>\n    <div class=\"byline\"><span class=\"avatar\" aria-hidden=\"true\">ME<\/span>\n      <span><strong>Mohamed El Hjouji<\/strong>Founder and CEO \u00b7 Updated <time datetime=\"2026-11-03\">November 3, 2026<\/time> \u00b7 Reading time 8 min<\/span><\/div>\n    <div class=\"actions\">\n      <a class=\"btn\" href=\"#consultation\">Create a betaine product <span class=\"knob\" aria-hidden=\"true\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.8\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/span><\/a>\n      <a class=\"btn-ghost\" href=\"#recherche\">Read the studies<\/a>\n    <\/div>\n  <\/div>\n  <figure class=\"hero-photo\"><img fetchpriority=\"high\" src=\"https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/betaine-ingredient-cosmetique-carmel.webp\" srcset=\"https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/betaine-ingredient-cosmetique-carmel-300x224.webp 300w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/betaine-ingredient-cosmetique-carmel-441x329.webp 441w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/betaine-ingredient-cosmetique-carmel-768x574.webp 768w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/betaine-ingredient-cosmetique-carmel-990x740.webp 990w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/betaine-ingredient-cosmetique-carmel-1024x765.webp 1024w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/betaine-ingredient-cosmetique-carmel.webp 1400w, https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/11\/betaine-ingredient-cosmetique-carmel.webp 1400w\" sizes=\"(max-width:900px) 92vw, 46vw\" width=\"1400\" height=\"1046\" alt=\"White betaine crystals in macro view on a sage green ceramic surface, with beetroot slices\" fetchpriority=\"high\" decoding=\"async\" title=\"| Carmel Cosmetics Labs\"><\/figure>\n<\/header>\n<div class=\"bar\" id=\"bar\"><div class=\"wrap bar-in\">\n  <nav aria-label=\"On this page\"><ul><li><a href=\"#identite\">Identity<\/a><\/li><li><a href=\"#recherche\">Research<\/a><\/li><li><a href=\"#produits\">Products<\/a><\/li><li><a href=\"#faq\">Questions<\/a><\/li><li><a href=\"#plus\">Reading<\/a><\/li><li><a href=\"#sources\">Sources<\/a><\/li><\/ul><\/nav>\n  <a class=\"btn sm\" href=\"#consultation\" tabindex=\"-1\">Create my product <span class=\"knob\" aria-hidden=\"true\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.8\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/span><\/a><\/div>\n  <span class=\"bar-prog\" id=\"prog\" aria-hidden=\"true\"><\/span><\/div>\n<section class=\"sec\" id=\"identite\" aria-labelledby=\"h-id\"><div class=\"wrap id-grid\">\n  <div><h2 class=\"h2\" id=\"h-id\">Betaine at a glance<\/h2>\n  <p class=\"lede\">Entry from our <a class=\"txt-link\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/\">cosmetic ingredient glossary<\/a>. Regulatory data from the European Commission's CosIng database<a class=\"ref\" href=\"#src-1\">1<\/a>. Copy the identifiers in one click for your files.<\/p><\/div>\n  <dl class=\"spec\"><div><dt>INCI name<\/dt><dd><span class=\"\">BETAINE<\/span><button class=\"copy\" type=\"button\" data-copy=\"BETAINE\" aria-label=\"Copy: INCI name\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><rect x=\"9\" y=\"9\" width=\"11\" height=\"11\" rx=\"2\"\/><path d=\"M5 15V5a2 2 0 0 1 2-2h8\"\/><\/svg>Copy<\/button><small>Not to be confused with COCAMIDOPROPYL BETAINE and the other alkyl betaines, which are surfactants<a class=\"ref\" href=\"#src-8\">8<\/a><a class=\"ref\" href=\"#src-9\">9<\/a><\/small><\/dd><\/div><div><dt>Other names<\/dt><dd>Trimethylglycine<small>Zwitterion (inner salt) according to CosIng<a class=\"ref\" href=\"#src-1\">1<\/a><\/small><\/dd><\/div><div><dt>CAS number<\/dt><dd><span class=\"num\">107-43-7 \/ 590-47-6<\/span><button class=\"copy\" type=\"button\" data-copy=\"107-43-7 \/ 590-47-6\" aria-label=\"Copy: CAS number\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><rect x=\"9\" y=\"9\" width=\"11\" height=\"11\" rx=\"2\"\/><path d=\"M5 15V5a2 2 0 0 1 2-2h8\"\/><\/svg>Copy<\/button><small>CosIng links two numbers to this entry<a class=\"ref\" href=\"#src-1\">1<\/a><\/small><\/dd><\/div><div><dt>EC number<\/dt><dd><span class=\"num\">203-490-6 \/ 209-684-7<\/span><button class=\"copy\" type=\"button\" data-copy=\"203-490-6 \/ 209-684-7\" aria-label=\"Copy: EC number\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><rect x=\"9\" y=\"9\" width=\"11\" height=\"11\" rx=\"2\"\/><path d=\"M5 15V5a2 2 0 0 1 2-2h8\"\/><\/svg>Copy<\/button><\/dd><\/div><div><dt>Formula<\/dt><dd class=\"num\">C\u2085H\u2081\u2081NO\u2082<small>Molar mass 117.15 g\/mol<\/small><\/dd><\/div><div><dt>CosIng functions<\/dt><dd>Humectant, hair conditioning<small>\"Humectant\", \"skin conditioning - humectant\" and \"hair conditioning\" in the European nomenclature<a class=\"ref\" href=\"#src-1\">1<\/a><\/small><\/dd><\/div><div><dt>Appearance<\/dt><dd>White crystalline powder<small>Very soluble in water, formulated in the aqueous phase<\/small><\/dd><\/div><div><dt>EU status<\/dt><dd>No restriction<small>Absent from Annexes II to VI of Regulation (EC) 1223\/2009<a class=\"ref\" href=\"#src-11\">11<\/a><\/small><\/dd><\/div><div><dt>Allergen to declare<\/dt><dd>No<small>Absent from the fragrance allergen list of Regulation (EU) 2023\/1545<\/small><\/dd><\/div><div><dt>Safety<\/dt><dd>No CIR opinion specific to betaine<small>CIR opinions cover surfactant alkyl betaines, not betaine alone<a class=\"ref\" href=\"#src-8\">8<\/a><a class=\"ref\" href=\"#src-9\">9<\/a><\/small><\/dd><\/div><\/dl><\/div><\/section>\n<section class=\"sec research\" id=\"recherche\" aria-labelledby=\"h-r\"><div class=\"wrap\">\n  <div class=\"r-head\"><div><h2 class=\"h2\" id=\"h-r\">What the research says<\/h2>\n  <p class=\"lede\">Each result shows the protocol and the level of evidence. The higher the level, the better the result carries over to a finished formula.<\/p><\/div><\/div>\n  <div class=\"r-tools\"><div class=\"seg\" role=\"group\" aria-label=\"Filter by area\" id=\"rfilter\"><button type=\"button\" aria-pressed=\"true\" data-d=\"all\">All <span>10<\/span><\/button><button type=\"button\" aria-pressed=\"false\" data-d=\"visage\">Face <span>4<\/span><\/button><button type=\"button\" aria-pressed=\"false\" data-d=\"corps\">Body <span>1<\/span><\/button><button type=\"button\" aria-pressed=\"false\" data-d=\"cheveux\">Hair <span>2<\/span><\/button><button type=\"button\" aria-pressed=\"false\" data-d=\"derm\">Safety <span>3<\/span><\/button><\/div><div class=\"legend\" aria-label=\"Levels of evidence\"><span class=\"lvl\"><i class=\"dot c\"><\/i>Clinical trial<\/span><span class=\"lvl\"><i class=\"dot r\"><\/i>Review or consensus<\/span><span class=\"lvl\"><i class=\"dot v\"><\/i>Laboratory<\/span><\/div><\/div>\n  <div class=\"domain\" data-d=\"visage\"><h3>Facial skin<span>Skincare<\/span><\/h3><div class=\"finds\"><article class=\"find\"><div class=\"find-top\"><h4>More barrier proteins in human skin<\/h4><span class=\"lvl\"><i class=\"dot v\"><\/i>Laboratory<\/span><\/div><div class=\"meta\"><span>Human skin in organ culture<\/span><span>Primary keratinocytes<\/span><span>Betaine and taurine<\/span><\/div><p>Skin expresses betaine transporters. When exposed to betaine or taurine, it produces more claudin-1, claudin-4 and occludin, which are tight junction proteins, and tight junction function increases in cultured keratinocytes. The effect disappears when the transporter is blocked<a class=\"ref\" href=\"#src-2\">2<\/a>.<\/p><\/article><article class=\"find\"><div class=\"find-top\"><h4>An effect on epidermal differentiation<\/h4><span class=\"lvl\"><i class=\"dot v\"><\/i>Laboratory<\/span><\/div><div class=\"meta\"><span>Betaine 10 mM<\/span><span>Rat keratinocytes, 3D culture<\/span><span>With or without UVB<\/span><\/div><p>Of 89 genes modified by betaine, keratin 2, a differentiation marker, is the most increased. The authors note that betaine is widely used in skincare despite the lack of studies on its own effects<a class=\"ref\" href=\"#src-3\">3<\/a>.<\/p><\/article><article class=\"find\"><div class=\"find-top\"><h4>Organic osmolytes protect tight junctions after UVB<\/h4><span class=\"lvl\"><i class=\"dot v\"><\/i>Laboratory<\/span><\/div><div class=\"meta\"><span>Rat keratinocytes<\/span><span>A single UVB dose<\/span><\/div><p>In the presence of organic osmolytes, the function of developing tight junctions is preserved after UVB. The effect does not go through cell volume or free radicals. The abstract does not say which osmolyte carries the effect: it applies to the betaine family, not to betaine alone<a class=\"ref\" href=\"#src-7\">7<\/a>.<\/p><\/article><article class=\"find\"><div class=\"find-top\"><h4>An aloe vera and trimethylglycine complex increases aquaporin 3<\/h4><span class=\"lvl\"><i class=\"dot v\"><\/i>Laboratory<\/span><\/div><div class=\"meta\"><span>Aloe vera and trimethylglycine 1:1<\/span><span>HaCaT keratinocytes<\/span><\/div><p>The complex increases aquaporin 3, a water channel of the epidermis, by up to 380% compared with the negative control. The effect is attributed to the combination, not to trimethylglycine alone<a class=\"ref\" href=\"#src-4\">4<\/a>.<\/p><\/article><\/div><\/div><div class=\"domain\" data-d=\"corps\"><h3>Body<span>Bodycare<\/span><\/h3><div class=\"finds\"><article class=\"find\"><div class=\"find-top\"><h4>A more hydrating shower gel, from the first use<\/h4><span class=\"lvl\"><i class=\"dot c\"><\/i>Clinical trial<\/span><\/div><div class=\"meta\"><span>Aloe vera and trimethylglycine shower gel<\/span><span>One use, then 28 days<\/span><span>Healthy volunteers<\/span><\/div><p>The shower gel improved skin hydration after one use and over 28 days, with good tolerance. The abstract gives neither the sample size nor the values, and the study does not separate trimethylglycine from aloe vera<a class=\"ref\" href=\"#src-4\">4<\/a>.<\/p><\/article><\/div><\/div><div class=\"domain\" data-d=\"cheveux\"><h3>Scalp and hair<span>Haircare<\/span><\/h3><div class=\"finds\"><article class=\"find\"><div class=\"find-top\"><h4>Betaine naturally present in hair<\/h4><span class=\"lvl\"><i class=\"dot v\"><\/i>Laboratory<\/span><\/div><div class=\"meta\"><span>HPLC assay<\/span><span>Human hair and blood<\/span><span>Preliminary study<\/span><\/div><p>Betaine can be measured in human hair. The authors show, in principle, that a shampoo can redeposit some on the fiber. They describe preliminary investigations, with no demonstrated effect on hair quality<a class=\"ref\" href=\"#src-5\">5<\/a>.<\/p><\/article><article class=\"find\"><div class=\"find-top\"><h4>Protection of a model protein under oxidative stress<\/h4><span class=\"lvl\"><i class=\"dot v\"><\/i>Laboratory<\/span><\/div><div class=\"meta\"><span>Betaine 0.50% w\/w<\/span><span>Bovine serum albumin<\/span><span>UV, pH, cold, oxidation<\/span><\/div><p>Of four osmolytes, only betaine protects the protein under oxidative stress. It also limits stress caused by cold, but increases it under UVA. A protein model, not hair: effects depend on the conditions<a class=\"ref\" href=\"#src-6\">6<\/a>.<\/p><\/article><\/div><\/div><div class=\"domain\" data-d=\"derm\"><h3>Safety and mix-ups<span>Regulation<\/span><\/h3><div class=\"finds\"><article class=\"find\"><div class=\"find-top\"><h4>Alkyl betaines: safe if formulated to be non-irritating<\/h4><span class=\"lvl\"><i class=\"dot r\"><\/i>Review<\/span><\/div><div class=\"meta\"><span>CIR panel 2018<\/span><span>11 alkyl betaines<\/span><\/div><p>The panel concludes that alkyl betaines, which are surfactants, are safe in current uses, provided they are formulated to be non-irritating. This report does not cover betaine alone<a class=\"ref\" href=\"#src-8\">8<\/a>.<\/p><\/article><article class=\"find\"><div class=\"find-top\"><h4>Cocamidopropyl betaine: the sensitizer is an impurity<\/h4><span class=\"lvl\"><i class=\"dot r\"><\/i>Review<\/span><\/div><div class=\"meta\"><span>CIR panel 2012<\/span><span>DMAPA and amidoamine impurities<\/span><\/div><p>The panel states that synthesis impurities (DMAPA, amidoamine) are known sensitizers. It judges these surfactants safe when formulated to be non-sensitizing<a class=\"ref\" href=\"#src-9\">9<\/a>.<\/p><\/article><article class=\"find\"><div class=\"find-top\"><h4>In people already sensitized, amidoamine is the culprit<\/h4><span class=\"lvl\"><i class=\"dot c\"><\/i>Patch test study<\/span><\/div><div class=\"meta\"><span>10 people with a positive patch test<\/span><span>Use for 1 to 6 weeks<\/span><span>Products with cocamidopropyl betaine<\/span><\/div><p>7 of 10 people reacted to at least one product. Of 9 tested afterward, 6 reacted to amidoamine. None reacted to amidoamine-free cocamidopropyl betaine<a class=\"ref\" href=\"#src-10\">10<\/a>.<\/p><\/article><\/div><\/div>\n  <p class=\"frame\">This page summarizes published literature on a cosmetic ingredient. It does not describe the effect of a finished product, which depends on its formula, and it is not medical advice. For betaine, the published data are laboratory results or trials on combined products: they do not prove the effect of betaine alone on skin. Two cited studies have an industry affiliation; this is noted in the sources.<\/p><\/div><\/section>\n\n<section class=\"sec products\" id=\"produits\" aria-labelledby=\"h-p\"><div class=\"wrap\">\n  <div class=\"p-head\"><div><h2 class=\"h2\" id=\"h-p\">Which products use betaine?<\/h2>\n  <p class=\"lede\">Our <a class=\"txt-link\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/personalized-cosmetics-products-catalog\/\">white label catalog<\/a> includes 5 formulas with betaine, always as a supporting ingredient. Every category can be customized (formula, fragrance, packaging).<\/p><\/div>\n  <div class=\"seg p-tabs\" role=\"tablist\" aria-label=\"Area\" id=\"ptabs\"><button type=\"button\" role=\"tab\" aria-selected=\"true\" aria-controls=\"pc-visage\" data-p=\"visage\">Face <span>1<\/span><\/button><button type=\"button\" role=\"tab\" aria-selected=\"false\" aria-controls=\"pc-corps\" data-p=\"corps\">Body <span>2<\/span><\/button><button type=\"button\" role=\"tab\" aria-selected=\"false\" aria-controls=\"pc-cheveux\" data-p=\"cheveux\">Hair <span>2<\/span><\/button><\/div><\/div>\n  <div class=\"p-cols\" style=\"--pc:3\"><div class=\"p-col on\" id=\"pc-visage\" role=\"tabpanel\"><h3><span class=\"count num\">1<\/span>Face<\/h3><p>Supporting active in a catalog micellar water.<\/p><ul><li><a href=\"https:\/\/carmelcosmeticslabs.com\/en\/personalized-cosmetics-products-catalog\/white-label-face-cleansers\/\"><span>Face cleansers<\/span><span class=\"n\">1<\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><\/ul><\/div><div class=\"p-col\" id=\"pc-corps\" role=\"tabpanel\"><h3><span class=\"count num\">2<\/span>Body<\/h3><p>Supporting active in a body mask and a shower oil.<\/p><ul><li><a href=\"https:\/\/carmelcosmeticslabs.com\/en\/personalized-cosmetics-products-catalog\/white-label-black-soap\/\"><span>Black soap and hammam<\/span><span class=\"n\">1<\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><li><a href=\"https:\/\/carmelcosmeticslabs.com\/en\/personalized-cosmetics-products-catalog\/white-label-shower-gels\/\"><span>Shower gels and soaps<\/span><span class=\"n\">1<\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><\/ul><\/div><div class=\"p-col\" id=\"pc-cheveux\" role=\"tabpanel\"><h3><span class=\"count num\">2<\/span>Hair<\/h3><p>Supporting active in a scalp spray and a shampoo.<\/p><ul><li><a href=\"https:\/\/carmelcosmeticslabs.com\/en\/personalized-cosmetics-products-catalog\/white-label-hair-serums\/\"><span>Hair serums and sprays<\/span><span class=\"n\">1<\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><li><a href=\"https:\/\/carmelcosmeticslabs.com\/en\/personalized-cosmetics-products-catalog\/white-label-shampoos\/\"><span>Shampoos and conditioners<\/span><span class=\"n\">1<\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><\/ul><\/div><\/div>\n  <div class=\"pairs\"><p>In our formulas, it is most often paired with<\/p><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/panthenol\/\">Panthenol <span class=\"num\">3<\/span><\/a><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/hyaluronic-acid\/\">Hyaluronic acid <span class=\"num\">2<\/span><\/a><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/urea\/\">Urea <span class=\"num\">2<\/span><\/a><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/allantoin\/\">Allantoin <span class=\"num\">1<\/span><\/a><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/aloe-vera\/\">Aloe vera <span class=\"num\">1<\/span><\/a><\/div>\n  <\/div><\/section>\n\n<section class=\"sec\" id=\"faq\" aria-labelledby=\"h-faq\"><div class=\"wrap faq-grid\">\n  <h2 class=\"h2\" id=\"h-faq\">Frequently asked questions about betaine<\/h2><div class=\"faq\"><details open><summary>What is betaine?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">It is trimethylglycine, an organic osmolyte: a small water-soluble molecule that helps cells hold on to their water. Skin expresses betaine transporters<a class=\"ref\" href=\"#src-2\">2<\/a>. In cosmetics, it is used as a humectant for skin and hair<a class=\"ref\" href=\"#src-1\">1<\/a>.<\/div><\/details><details><summary>Is betaine the same as cocamidopropyl betaine?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">No. Betaine (INCI BETAINE) is an osmolyte. Cocamidopropyl betaine is an amphoteric cleansing surfactant with a different INCI name. CIR opinions cover the surfactants<a class=\"ref\" href=\"#src-8\">8<\/a><a class=\"ref\" href=\"#src-9\">9<\/a>, and the allergic reactions described are attributed mainly to amidoamine, an impurity<a class=\"ref\" href=\"#src-10\">10<\/a>. This page covers betaine alone.<\/div><\/details><details><summary>What are the benefits of betaine for skin?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">It is used to hydrate and to help maintain the skin barrier. Evidence is limited: in the laboratory, it increases tight junction proteins<a class=\"ref\" href=\"#src-2\">2<\/a>; a shower gel combining trimethylglycine and aloe vera improves hydration, without isolating betaine<a class=\"ref\" href=\"#src-4\">4<\/a>. No clinical trial tests betaine alone.<\/div><\/details><details><summary>What percentage of betaine should you use?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">No cited study gives a clinical trial concentration for betaine alone. Laboratory work uses 10 mM on cells<a class=\"ref\" href=\"#src-3\">3<\/a> and 0.50% w\/w on a model protein<a class=\"ref\" href=\"#src-6\">6<\/a>. The dose of a product is set with the formulator, depending on the format and the target.<\/div><\/details><details><summary>Is betaine good for hair?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">It is naturally present in hair, and a shampoo can redeposit some, according to a preliminary study<a class=\"ref\" href=\"#src-5\">5<\/a>. No result on hair appearance or strength has been published. It remains a supporting active in shampoos and hair sprays.<\/div><\/details><details><summary>Is betaine safe?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">It is not restricted in the EU<a class=\"ref\" href=\"#src-11\">11<\/a> and is not a fragrance allergen to declare. The allergy cases described concern cocamidopropyl betaine and its impurities<a class=\"ref\" href=\"#src-10\">10<\/a>, not betaine. During pregnancy, as with any skincare product, a healthcare professional's advice remains the rule.<\/div><\/details><details><summary>Can you manufacture a betaine product for my brand?<svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" aria-hidden=\"true\"><path d=\"M12 5v14M5 12h14\"\/><\/svg><\/summary><div class=\"a\">Yes. Our <a class=\"txt-link\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/iso-22716-certified-cosmetics-manufacturer\/\">ISO 22716 certified<\/a> laboratory offers 5 formulas containing betaine (face cleanser, body and hair care) to customize, or a <a class=\"txt-link\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/cosmetic-formulation-lab\/\">custom formula<\/a>. Free samples are included.<\/div><\/details><\/div><\/div><\/section>\n<section class=\"sec\" id=\"plus\" aria-labelledby=\"h-more\" style=\"padding-top:0\"><div class=\"wrap more-grid\">\n  <div><h2 class=\"h2\" id=\"h-more\">Further reading<\/h2><div class=\"hubs\"><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/\">Ingredient glossary<\/a><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/personalized-cosmetics-products-catalog\/white-label-face-cleansers\/\">White label face cleansers<\/a><a class=\"chip\" href=\"https:\/\/carmelcosmeticslabs.com\/en\/cosmetic-formulation-lab\/\">Cosmetic formulation lab<\/a><\/div><\/div>\n  <ul class=\"more-list\"><li><a href=\"https:\/\/carmelcosmeticslabs.com\/en\/trending-cosmetic-ingredients-2026\/\"><span><strong>Top 10 trending cosmetic ingredients in 2026<\/strong><small>The actives to add to a white label range<\/small><\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><li><a href=\"https:\/\/carmelcosmeticslabs.com\/en\/natural-vs-synthetic-cosmetics\/\"><span><strong>Natural vs synthetic cosmetics: pros and limits<\/strong><small>Plant-based or synthetic origin: a look at both approaches<\/small><\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><li><a href=\"https:\/\/carmelcosmeticslabs.com\/en\/eu-cosmetics-regulations-2026\/\"><span><strong>EU cosmetics regulations in 2026<\/strong><small>The regulatory framework to know before launching a range<\/small><\/span><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/a><\/li><\/ul><\/div><\/section>\n<section class=\"sec sources\" id=\"sources\" aria-labelledby=\"h-s\"><div class=\"wrap\">\n  <h2 class=\"h2\" id=\"h-s\">Sources<\/h2><p class=\"lede\">Peer-reviewed studies and official regulatory sources, checked on November 3, 2026.<\/p>\n  <ol class=\"src\"><li id=\"src-1\"><span>European Commission. <em>CosIng, entry BETAINE<\/em> (CAS 107-43-7 \/ 590-47-6, CE 203-490-6 \/ 209-684-7). <a class=\"txt-link\" href=\"https:\/\/ec.europa.eu\/growth\/tools-databases\/cosing\/details\/74520\" target=\"_blank\" rel=\"noopener\">ec.europa.eu\/growth\/tools-databases\/cosing<\/a><\/span><\/li><li id=\"src-2\"><span>El-Chami C, Foster AR, Johnson C, et al. <em>Organic osmolytes increase expression of specific tight junction proteins in skin and alter barrier function in keratinocytes.<\/em> Br J Dermatol. 2021;184(3):482-494. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1111\/bjd.19162\" target=\"_blank\" rel=\"noopener\">doi:10.1111\/bjd.19162<\/a><\/span><\/li><li id=\"src-3\"><span>Rauhala L, H\u00e4m\u00e4l\u00e4inen L, Dunlop TW, et al. <em>The organic osmolyte betaine induces keratin 2 expression in rat epidermal keratinocytes - A genome-wide study in UVB irradiated organotypic 3D cultures.<\/em> Toxicol In Vitro. 2015;30(1 Pt B):462-475. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1016\/j.tiv.2015.09.015\" target=\"_blank\" rel=\"noopener\">doi:10.1016\/j.tiv.2015.09.015<\/a><\/span><\/li><li id=\"src-4\"><span>Filatov V, Sokolova A, Savitskaya N, et al. <em>Synergetic effects of aloe vera extract with trimethylglycine for targeted aquaporin 3 regulation and long-term skin hydration.<\/em> Molecules. 2024;29(7):1540. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.3390\/molecules29071540\" target=\"_blank\" rel=\"noopener\">doi:10.3390\/molecules29071540<\/a><span class=\"tag\">SkyLab AG<\/span><\/span><\/li><li id=\"src-5\"><span>Pulliainen K, Nevalainen H, V\u00e4kev\u00e4inen H, et al. <em>An analytical method for the determination of betaine (trimethylglycine) from hair.<\/em> Int J Cosmet Sci. 2010;32(2):135-138. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1111\/j.1468-2494.2009.00554.x\" target=\"_blank\" rel=\"noopener\">doi:10.1111\/j.1468-2494.2009.00554.x<\/a><span class=\"tag\">Finnfeeds (Danisco)<\/span><\/span><\/li><li id=\"src-6\"><span>Sinesi G, Salvioni L, Ronchi E, et al. <em>Exploring bovine serum albumin (BSA) as a facile substrate for testing of osmolytes as cosmetic ingredients.<\/em> Molecules. 2025;30(3):664. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.3390\/molecules30030664\" target=\"_blank\" rel=\"noopener\">doi:10.3390\/molecules30030664<\/a><\/span><\/li><li id=\"src-7\"><span>El-Chami C, Haslam IS, Steward MC, et al. <em>Organic osmolytes preserve the function of the developing tight junction in ultraviolet B-irradiated rat epidermal keratinocytes.<\/em> Sci Rep. 2018;8(1):5167. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1038\/s41598-018-22533-0\" target=\"_blank\" rel=\"noopener\">doi:10.1038\/s41598-018-22533-0<\/a><\/span><\/li><li id=\"src-8\"><span>Burnett CL, Bergfeld WF, Belsito DV, et al. <em>Safety assessment of alkyl betaines as used in cosmetics.<\/em> Int J Toxicol. 2018;37(1_suppl):28S-46S. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1177\/1091581818773354\" target=\"_blank\" rel=\"noopener\">doi:10.1177\/1091581818773354<\/a><\/span><\/li><li id=\"src-9\"><span>Burnett CL, Bergfeld WF, Belsito DV, et al. <em>Final report of the Cosmetic Ingredient Review Expert Panel on the safety assessment of cocamidopropyl betaine (CAPB).<\/em> Int J Toxicol. 2012;31(4 Suppl):77S-111S. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1177\/1091581812447202\" target=\"_blank\" rel=\"noopener\">doi:10.1177\/1091581812447202<\/a><\/span><\/li><li id=\"src-10\"><span>Fowler JF, Fowler LM, Hunter JE. <em>Allergy to cocamidopropyl betaine may be due to amidoamine: a patch test and product use test study.<\/em> Contact Dermatitis. 1997;37(6):276-281. <a class=\"txt-link\" href=\"https:\/\/doi.org\/10.1111\/j.1600-0536.1997.tb02464.x\" target=\"_blank\" rel=\"noopener\">doi:10.1111\/j.1600-0536.1997.tb02464.x<\/a><\/span><\/li><li id=\"src-11\"><span>European Parliament and Council. <em>Regulation (EC) No 1223\/2009 on cosmetic products<\/em>, consolidated version of May 1, 2025: Annexes II to VI. <a class=\"txt-link\" href=\"https:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/?uri=CELEX:02009R1223-20250501\" target=\"_blank\" rel=\"noopener\">eur-lex.europa.eu<\/a><\/span><\/li><\/ol><\/div><\/section>\n\n<div class=\"fab\" id=\"fab\"><a class=\"btn\" href=\"#consultation\">Create a betaine product <span class=\"knob\" aria-hidden=\"true\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.8\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><path d=\"M5 12h14M13 6l6 6-6 6\"\/><\/svg><\/span><\/a><\/div><div class=\"scrim\" id=\"scrim\"><\/div><div class=\"pop\" id=\"pop\" role=\"dialog\" aria-modal=\"false\" aria-labelledby=\"pop-n\" hidden><div class=\"pop-n\" id=\"pop-n\"><\/div><div class=\"pop-body\" id=\"pop-body\"><\/div><div class=\"pop-foot\"><a class=\"txt-link\" id=\"pop-all\" href=\"#sources\">All sources<\/a><button class=\"pop-x\" type=\"button\" id=\"pop-x\">Close<\/button><\/div><\/div>\n<\/div>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@graph\": [{\"@type\": \"WebPage\", \"@id\": \"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/betaine\/#webpage\", \"url\": \"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/betaine\/\", \"name\": \"Betaine in Cosmetics: INCI, Studies and Uses\", \"inLanguage\": \"en-US\", \"datePublished\": \"2026-11-03\", \"dateModified\": \"2026-11-03\", \"author\": {\"@type\": \"Person\", \"name\": \"Mohamed El Hjouji\", \"jobTitle\": \"Founder and CEO\", \"worksFor\": {\"@type\": \"Organization\", \"name\": \"Carmel Cosmetics Labs\", \"url\": \"https:\/\/carmelcosmeticslabs.com\/\"}}, \"about\": {\"@type\": \"ChemicalSubstance\", \"name\": \"Betaine\", \"alternateName\": [\"Trimethylglycine\", \"Betaine\"], \"chemicalComposition\": \"C5H11NO2\", \"identifier\": \"CAS 107-43-7\"}, \"mainEntity\": {\"@id\": \"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/betaine\/#term\"}, \"isPartOf\": {\"@type\": \"CollectionPage\", \"name\": \"Cosmetic ingredient glossary\", \"url\": \"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/\"}, \"relatedLink\": [\"https:\/\/carmelcosmeticslabs.com\/en\/trending-cosmetic-ingredients-2026\/\", \"https:\/\/carmelcosmeticslabs.com\/en\/natural-vs-synthetic-cosmetics\/\", \"https:\/\/carmelcosmeticslabs.com\/en\/eu-cosmetics-regulations-2026\/\"], \"citation\": 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of the Cosmetic Ingredient Review Expert Panel on the safety assessment of cocamidopropyl betaine (CAPB)\", \"sameAs\": \"https:\/\/doi.org\/10.1177\/1091581812447202\", \"datePublished\": \"2012\"}, {\"@type\": \"ScholarlyArticle\", \"name\": \"Allergy to cocamidopropyl betaine may be due to amidoamine: a patch test and product use test study\", \"sameAs\": \"https:\/\/doi.org\/10.1111\/j.1600-0536.1997.tb02464.x\", \"datePublished\": \"1997\"}, {\"@type\": \"Legislation\", \"name\": \"Regulation (EC) No 1223\/2009, consolidated version\", \"url\": \"https:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/?uri=CELEX:02009R1223-20250501\"}]}, {\"@type\": \"DefinedTerm\", \"@id\": \"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/betaine\/#term\", \"name\": \"Betaine\", \"alternateName\": \"BETAINE\", \"description\": \"Water-soluble organic osmolyte, used in cosmetics as a humectant for skin and hair.\", \"inDefinedTermSet\": {\"@type\": \"DefinedTermSet\", \"name\": \"Cosmetic ingredient glossary\", \"url\": \"https:\/\/carmelcosmeticslabs.com\/en\/glossary-cosmetic-ingredients\/\"}}, {\"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"What is betaine?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"It is trimethylglycine, an organic osmolyte: a small water-soluble molecule that helps cells hold on to their water. Skin expresses betaine transporters. In cosmetics, it is used as a humectant for skin and hair.\"}}, {\"@type\": \"Question\", \"name\": \"Is betaine the same as cocamidopropyl betaine?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"No. Betaine (INCI BETAINE) is an osmolyte. Cocamidopropyl betaine is an amphoteric cleansing surfactant with a different INCI name. CIR opinions cover the surfactants, and the allergic reactions described are attributed mainly to amidoamine, an impurity. This page covers betaine alone.\"}}, {\"@type\": \"Question\", \"name\": \"What are the benefits of betaine for skin?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"It is used to hydrate and to help maintain the skin barrier. Evidence is limited: in the laboratory, it increases tight junction proteins; a shower gel combining trimethylglycine and aloe vera improves hydration, without isolating betaine. No clinical trial tests betaine alone.\"}}, {\"@type\": \"Question\", \"name\": \"What percentage of betaine should you use?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"No cited study gives a clinical trial concentration for betaine alone. Laboratory work uses 10 mM on cells and 0.50% w\/w on a model protein. The dose of a product is set with the formulator, depending on the format and the target.\"}}, {\"@type\": \"Question\", \"name\": \"Is betaine good for hair?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"It is naturally present in hair, and a shampoo can redeposit some, according to a preliminary study. No result on hair appearance or strength has been published. It remains a supporting active in shampoos and hair sprays.\"}}, {\"@type\": \"Question\", \"name\": \"Is betaine safe?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"It is not restricted in the EU and is not a fragrance allergen to declare. The allergy cases described concern cocamidopropyl betaine and its impurities, not betaine. During pregnancy, as with any skincare product, a healthcare professional's advice remains the rule.\"}}, {\"@type\": \"Question\", \"name\": \"Can you manufacture a betaine product for my brand?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Yes. Our ISO 22716 certified laboratory offers 5 formulas containing betaine (face cleanser, body and hair care) to customize, or a custom formula. 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.wpforms-confirmation-container-full{background:var(--mint)!important;border:0!important;border-radius:18px!important;color:var(--ink)!important;padding:22px!important}\n@media (max-width:520px){body .lpf-card .wpforms-field-name .wpforms-field-row{grid-template-columns:1fr}}\n<\/style><div class=\"dv-card-head\"><img loading=\"lazy\" class=\"dv-avatar\" src=\"https:\/\/carmelcosmeticslabs.com\/wp-content\/uploads\/2026\/09\/lancer-marque-cosmetique-etape-1-expert-carmel-768x953.webp\" alt=\"Carmel Cosmetics Labs product specialist with a brand founder\" width=\"768\" height=\"953\" loading=\"lazy\" decoding=\"async\" title=\"| Carmel Cosmetics Labs\"><div><h2>Tell us about your project<\/h2><p>A product specialist reviews your request and gets back to you on the channel you prefer.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-018bd53 dv-form eael-wpforms-labels-yes eael-wpforms-form-button-custom elementor-widget elementor-widget-eael-wpforms\" data-id=\"018bd53\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-wpforms.default\">\n\t\t\t\t\t            <div class=\"eael-contact-form eael-wpforms eael-wpforms-align-default\">\n                                <div class=\"wpforms-container wpforms-container-full wpforms-render-modern\" id=\"wpforms-28270\"><form id=\"wpforms-form-28270\" class=\"wpforms-validate wpforms-form wpforms-ajax-form\" data-formid=\"28270\" method=\"post\" enctype=\"multipart\/form-data\" action=\"\/en\/wp-json\/wp\/v2\/pages\/55611\" data-token=\"1a6c3a68ef8f7b7f2f6489a2cc53529c\" data-token-time=\"1794233804\"><div class=\"wpforms-head-container\"><div class=\"wpforms-title\">Lead EN \u2013 Demande de devis<\/div><div class=\"wpforms-description\">Tell us about your project. A product specialist will get back to you shortly.<\/div><\/div><noscript class=\"wpforms-error-noscript\">Please enable JavaScript in your browser to complete this form.<\/noscript><div id=\"wpforms-error-noscript\" style=\"display: none;\">Please enable JavaScript in your browser to complete this form.<\/div><div class=\"wpforms-field-container\"><div id=\"wpforms-28270-field_26-container\" class=\"wpforms-field wpforms-field-html\" data-field-type=\"html\" data-field-id=\"26\"><div id=\"wpforms-28270-field_26\" aria-errormessage=\"wpforms-28270-field_26-error\"><center>CONTACT INFORMATION<\/center><\/div><\/div><div id=\"wpforms-28270-field_8-container\" class=\"wpforms-field wpforms-field-name\" data-field-type=\"name\" data-field-id=\"8\"><fieldset><legend class=\"wpforms-field-label wpforms-label-hide\" aria-hidden=\"false\">Name <span class=\"wpforms-required-label\" aria-hidden=\"true\">*<\/span><\/legend><div class=\"wpforms-field-row wpforms-field-large\"><div 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data-field-id=\"10\"><div class=\"wpforms-field-layout-columns wpforms-field-layout-preset-50-50\"><div class=\"wpforms-layout-column wpforms-layout-column-50\" ><div id=\"wpforms-28270-field_9-container\" class=\"wpforms-field wpforms-field-email\" data-field-type=\"email\" data-field-id=\"9\"><label class=\"wpforms-field-label wpforms-label-hide\" for=\"wpforms-28270-field_9\" aria-hidden=\"false\">Email <span class=\"wpforms-required-label\" aria-hidden=\"true\">*<\/span><\/label><input type=\"email\" id=\"wpforms-28270-field_9\" class=\"wpforms-field-medium wpforms-field-required\" name=\"wpforms[fields][9]\" placeholder=\"Email\" spellcheck=\"false\" aria-errormessage=\"wpforms-28270-field_9-error\" required><\/div><div id=\"wpforms-28270-field_39-container\" class=\"wpforms-field wpforms-field-select wpforms-field-select-style-modern\" data-field-type=\"select\" data-field-id=\"39\"><label class=\"wpforms-field-label\" for=\"wpforms-28270-field_39\">Preferred Contact Method<\/label><select id=\"wpforms-28270-field_39\" class=\"wpforms-field-medium choicesjs-select\" data-size-class=\"wpforms-field-row wpforms-field-medium\" data-search-enabled=\"\" name=\"wpforms[fields][39]\"><option value=\"\" class=\"placeholder\" disabled  selected='selected'>Please select your preferred method of contact<\/option><option value=\"WhatsApp\"  class=\"choice-1 depth-1\"  >WhatsApp<\/option><option value=\"Email\"  class=\"choice-2 depth-1\"  >Email<\/option><option value=\"Call only\"  class=\"choice-3 depth-1\"  >Call only<\/option><\/select><\/div><\/div><div class=\"wpforms-layout-column wpforms-layout-column-50\" ><div id=\"wpforms-28270-field_11-container\" class=\"wpforms-field wpforms-field-phone\" data-field-type=\"phone\" data-field-id=\"11\"><label class=\"wpforms-field-label wpforms-label-hide\" for=\"wpforms-28270-field_11\" aria-hidden=\"false\">Phone <span class=\"wpforms-required-label\" aria-hidden=\"true\">*<\/span><\/label><input type=\"tel\" id=\"wpforms-28270-field_11\" class=\"wpforms-field-medium wpforms-field-required wpforms-smart-phone-field\" data-rule-smart-phone-field=\"true\" name=\"wpforms[fields][11]\" placeholder=\"Phone\" aria-label=\"Phone\" aria-errormessage=\"wpforms-28270-field_11-error\" required><\/div><div id=\"wpforms-28270-field_13-container\" class=\"wpforms-field wpforms-field-text\" data-field-type=\"text\" data-field-id=\"13\"><label class=\"wpforms-field-label wpforms-label-hide\" for=\"wpforms-28270-field_13\" aria-hidden=\"false\">Company or brand name \/ website<\/label><input type=\"text\" id=\"wpforms-28270-field_13\" class=\"wpforms-field-medium\" name=\"wpforms[fields][13]\" placeholder=\"Company or brand name \/ website\" aria-errormessage=\"wpforms-28270-field_13-error\" ><\/div><\/div><\/div><\/div><div id=\"wpforms-28270-field_27-container\" class=\"wpforms-field wpforms-field-html\" data-field-type=\"html\" data-field-id=\"27\"><div id=\"wpforms-28270-field_27\" aria-errormessage=\"wpforms-28270-field_27-error\"><center>PROJECT INFORMATION<\/center><\/div><\/div><div id=\"wpforms-28270-field_35-container\" class=\"wpforms-field wpforms-field-checkbox wpforms-list-2-columns\" data-field-type=\"checkbox\" data-field-id=\"35\"><fieldset><legend class=\"wpforms-field-label\">Which cosmetics category interests you most? <span class=\"wpforms-required-label\" aria-hidden=\"true\">*<\/span><\/legend><ul id=\"wpforms-28270-field_35\" class=\"wpforms-field-required\"><li class=\"choice-1 depth-1\"><input type=\"checkbox\" id=\"wpforms-28270-field_35_1\" name=\"wpforms[fields][35][]\" value=\"Face care Products\" aria-errormessage=\"wpforms-28270-field_35_1-error\" required ><label class=\"wpforms-field-label-inline\" for=\"wpforms-28270-field_35_1\">Face care Products<\/label><\/li><li class=\"choice-2 depth-1\"><input type=\"checkbox\" id=\"wpforms-28270-field_35_2\" name=\"wpforms[fields][35][]\" value=\"Haircare Products\" aria-errormessage=\"wpforms-28270-field_35_2-error\" required ><label class=\"wpforms-field-label-inline\" for=\"wpforms-28270-field_35_2\">Haircare Products<\/label><\/li><li class=\"choice-3 depth-1\"><input type=\"checkbox\" id=\"wpforms-28270-field_35_3\" name=\"wpforms[fields][35][]\" value=\"Bodycare Products\" aria-errormessage=\"wpforms-28270-field_35_3-error\" required ><label class=\"wpforms-field-label-inline\" for=\"wpforms-28270-field_35_3\">Bodycare Products<\/label><\/li><li class=\"choice-4 depth-1\"><input type=\"checkbox\" id=\"wpforms-28270-field_35_4\" name=\"wpforms[fields][35][]\" value=\"Lipcare Products\" aria-errormessage=\"wpforms-28270-field_35_4-error\" required ><label class=\"wpforms-field-label-inline\" for=\"wpforms-28270-field_35_4\">Lipcare Products<\/label><\/li><li class=\"choice-5 depth-1\"><input type=\"checkbox\" id=\"wpforms-28270-field_35_5\" name=\"wpforms[fields][35][]\" value=\"Men&#039;s grooming Products\" aria-errormessage=\"wpforms-28270-field_35_5-error\" required ><label class=\"wpforms-field-label-inline\" for=\"wpforms-28270-field_35_5\">Men's grooming Products<\/label><\/li><li class=\"choice-6 depth-1\"><input type=\"checkbox\" id=\"wpforms-28270-field_35_6\" name=\"wpforms[fields][35][]\" value=\"Niche Products\" aria-errormessage=\"wpforms-28270-field_35_6-error\" required ><label class=\"wpforms-field-label-inline\" for=\"wpforms-28270-field_35_6\">Niche Products<\/label><\/li><li class=\"choice-7 depth-1\"><input type=\"checkbox\" id=\"wpforms-28270-field_35_7\" name=\"wpforms[fields][35][]\" value=\"Intimate Products\" aria-errormessage=\"wpforms-28270-field_35_7-error\" required ><label class=\"wpforms-field-label-inline\" for=\"wpforms-28270-field_35_7\">Intimate Products<\/label><\/li><li class=\"choice-8 depth-1\"><input type=\"checkbox\" id=\"wpforms-28270-field_35_8\" name=\"wpforms[fields][35][]\" value=\"Others\" aria-errormessage=\"wpforms-28270-field_35_8-error\" required ><label class=\"wpforms-field-label-inline\" for=\"wpforms-28270-field_35_8\">Others<\/label><\/li><\/ul><\/fieldset><\/div><div id=\"wpforms-28270-field_30-container\" class=\"wpforms-field wpforms-field-select wpforms-field-select-style-modern\" data-field-type=\"select\" data-field-id=\"30\"><label class=\"wpforms-field-label\" for=\"wpforms-28270-field_30\">What would be the quantity of your order per product? <span class=\"wpforms-required-label\" aria-hidden=\"true\">*<\/span><\/label><select id=\"wpforms-28270-field_30\" class=\"wpforms-field-large wpforms-field-required choicesjs-select\" data-size-class=\"wpforms-field-row wpforms-field-large\" data-search-enabled=\"\" name=\"wpforms[fields][30]\" required=\"required\"><option value=\"\" class=\"placeholder\" disabled  selected='selected'><\/option><option value=\"less than 1000 units\"  class=\"choice-1 depth-1\"  >less than 1000 units<\/option><option value=\"1000 - 5000 units\"  class=\"choice-3 depth-1\"  >1000 - 5000 units<\/option><option value=\"5000 - 10000 units\"  class=\"choice-6 depth-1\"  >5000 - 10000 units<\/option><option value=\"10000 - 50000 units\"  class=\"choice-7 depth-1\"  >10000 - 50000 units<\/option><option value=\"more than 50000 units\"  class=\"choice-4 depth-1\"  >more than 50000 units<\/option><option value=\"Not sure yet\"  class=\"choice-8 depth-1\"  >Not sure yet<\/option><\/select><\/div><div id=\"wpforms-28270-field_22-container\" class=\"wpforms-field wpforms-field-textarea\" data-field-type=\"textarea\" data-field-id=\"22\"><label class=\"wpforms-field-label\" for=\"wpforms-28270-field_22\">Please describe your project?<\/label><textarea id=\"wpforms-28270-field_22\" class=\"wpforms-field-medium\" name=\"wpforms[fields][22]\" placeholder=\"Your products and objectives? Detailed cosmetic product specifications? A link to download your reference files or images? Or anything else that might help us better understand your project.\" aria-errormessage=\"wpforms-28270-field_22-error\" ><\/textarea><\/div><div id=\"wpforms-28270-field_24-container\" class=\"wpforms-field wpforms-field-content\" data-field-type=\"content\" data-field-id=\"24\"><div id=\"wpforms-28270-field_24\" class=\"wpforms-field-large wpforms-field-row\" aria-errormessage=\"wpforms-28270-field_24-error\"><p>By submitting this form, you agree to our terms of service and privacy policy.<\/p>\n<div class=\"wpforms-field-content-display-frontend-clear\"><\/div><\/div><\/div><div id=\"wpforms-28270-field_52-container\" class=\"wpforms-field wpforms-field-hidden ccl-utm_source\" data-field-type=\"hidden\" data-field-id=\"52\"><input type=\"hidden\" id=\"wpforms-28270-field_52\" name=\"wpforms[fields][52]\"><\/div><div id=\"wpforms-28270-field_53-container\" class=\"wpforms-field wpforms-field-hidden ccl-utm_medium\" data-field-type=\"hidden\" data-field-id=\"53\"><input type=\"hidden\" id=\"wpforms-28270-field_53\" name=\"wpforms[fields][53]\"><\/div><div id=\"wpforms-28270-field_54-container\" class=\"wpforms-field wpforms-field-hidden ccl-utm_campaign\" data-field-type=\"hidden\" data-field-id=\"54\"><input type=\"hidden\" id=\"wpforms-28270-field_54\" name=\"wpforms[fields][54]\"><\/div><div id=\"wpforms-28270-field_55-container\" class=\"wpforms-field wpforms-field-hidden ccl-utm_term\" data-field-type=\"hidden\" data-field-id=\"55\"><input type=\"hidden\" id=\"wpforms-28270-field_55\" name=\"wpforms[fields][55]\"><\/div><div id=\"wpforms-28270-field_56-container\" class=\"wpforms-field wpforms-field-hidden ccl-utm_content\" data-field-type=\"hidden\" data-field-id=\"56\"><input type=\"hidden\" id=\"wpforms-28270-field_56\" name=\"wpforms[fields][56]\"><\/div><div id=\"wpforms-28270-field_57-container\" class=\"wpforms-field wpforms-field-hidden ccl-gclid\" data-field-type=\"hidden\" data-field-id=\"57\"><input type=\"hidden\" id=\"wpforms-28270-field_57\" name=\"wpforms[fields][57]\"><\/div><div id=\"wpforms-28270-field_58-container\" class=\"wpforms-field wpforms-field-hidden ccl-gbraid\" data-field-type=\"hidden\" data-field-id=\"58\"><input type=\"hidden\" id=\"wpforms-28270-field_58\" name=\"wpforms[fields][58]\"><\/div><div id=\"wpforms-28270-field_59-container\" class=\"wpforms-field wpforms-field-hidden ccl-wbraid\" data-field-type=\"hidden\" data-field-id=\"59\"><input type=\"hidden\" id=\"wpforms-28270-field_59\" name=\"wpforms[fields][59]\"><\/div><div id=\"wpforms-28270-field_60-container\" class=\"wpforms-field wpforms-field-hidden ccl-fbclid\" data-field-type=\"hidden\" data-field-id=\"60\"><input type=\"hidden\" id=\"wpforms-28270-field_60\" name=\"wpforms[fields][60]\"><\/div><div id=\"wpforms-28270-field_61-container\" class=\"wpforms-field wpforms-field-hidden ccl-landing\" data-field-type=\"hidden\" data-field-id=\"61\"><input type=\"hidden\" id=\"wpforms-28270-field_61\" name=\"wpforms[fields][61]\"><\/div><div id=\"wpforms-28270-field_62-container\" class=\"wpforms-field wpforms-field-hidden ccl-referrer\" data-field-type=\"hidden\" data-field-id=\"62\"><input type=\"hidden\" id=\"wpforms-28270-field_62\" name=\"wpforms[fields][62]\"><\/div><div id=\"wpforms-28270-field_63-container\" class=\"wpforms-field wpforms-field-hidden ccl-first_touch\" data-field-type=\"hidden\" data-field-id=\"63\"><input type=\"hidden\" id=\"wpforms-28270-field_63\" name=\"wpforms[fields][63]\"><\/div><div id=\"wpforms-28270-field_64-container\" class=\"wpforms-field wpforms-field-hidden ccl-canal\" data-field-type=\"hidden\" data-field-id=\"64\"><input type=\"hidden\" id=\"wpforms-28270-field_64\" name=\"wpforms[fields][64]\"><\/div><div id=\"wpforms-28270-field_65-container\" class=\"wpforms-field wpforms-field-hidden ccl-campagne\" data-field-type=\"hidden\" data-field-id=\"65\"><input type=\"hidden\" id=\"wpforms-28270-field_65\" name=\"wpforms[fields][65]\"><\/div><\/div><!-- .wpforms-field-container --><div class=\"wpforms-submit-container\" ><input type=\"hidden\" name=\"wpforms[id]\" value=\"28270\"><input type=\"hidden\" name=\"wpforms[time_token]\" value=\"1794233804.e99408b949b1999bb79bdbb2417f75e1b473f08869bc52da5a22e03951943b9a\"><input type=\"hidden\" name=\"page_title\" value=\"\"><input type=\"hidden\" name=\"page_url\" value=\"https:\/\/carmelcosmeticslabs.com\/en\/wp-json\/wp\/v2\/pages\/55611\"><input type=\"hidden\" name=\"url_referer\" value=\"\"><button type=\"submit\" name=\"wpforms[submit]\" id=\"wpforms-submit-28270\" class=\"wpforms-submit\" data-alt-text=\"Sending...\" data-submit-text=\"Get my free consultation\" aria-live=\"assertive\" value=\"wpforms-submit\">Get my free consultation<\/button><img decoding=\"async\" src=\"https:\/\/carmelcosmeticslabs.com\/wp-content\/plugins\/wpforms\/assets\/images\/submit-spin.svg\" class=\"wpforms-submit-spinner\" style=\"display: none;\" width=\"26\" height=\"26\" alt=\"Loading\" title=\"| Carmel Cosmetics Labs\"><\/div><\/form><\/div>  <!-- .wpforms-container -->            <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-94f5e5c elementor-widget elementor-widget-html\" data-id=\"94f5e5c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<p class=\"dv-reassure\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\"><rect x=\"4\" y=\"11\" width=\"16\" height=\"10\" rx=\"2\"\/><path d=\"M8 11V7a4 4 0 0 1 8 0v4\"\/><\/svg>No obligation. Your information stays confidential and is used only to prepare your quote.<\/p><script>(function(){var s=document.getElementById('consultation');if(!s)return;\nvar re=\/\\\/(demande-de-devis|request-a-quote|kostenvoranschlag-anfordern|%d8%b7%d9%84%d8%a8-%d8%a7%d9%82%d8%aa%d8%a8%d8%a7%d8%b3|\u0637\u0644\u0628-\u0627\u0642\u062a\u0628\u0627\u0633)\\\/?([?#].*)?$\/i;\nvar root=s.closest('[data-elementor-type=\"wp-page\"]')||document;\nroot.querySelectorAll('a[href]').forEach(function(a){var h=a.getAttribute('href')||'',d=h;try{d=decodeURIComponent(h);}catch(e){}if(re.test(h)||re.test(d)){a.setAttribute('href','#consultation');}});\ndocument.addEventListener('click',function(e){var a=e.target.closest&&e.target.closest('a[href=\"#consultation\"]');if(!a)return;e.preventDefault();\nvar sm=!matchMedia('(prefers-reduced-motion: reduce)').matches;s.scrollIntoView({behavior:sm?'smooth':'auto',block:'start'});\nvar f=s.querySelector('form input:not([type=hidden]),form select,form textarea');\nvar off=function(){return Math.abs(s.getBoundingClientRect().top-110)>24},fix=function(){if(off())s.scrollIntoView({behavior:'auto',block:'start'});setTimeout(function(){if(off())s.scrollIntoView({behavior:'auto',block:'start'});if(f)try{f.focus({preventScroll:true})}catch(_){}},350)};\nvar last=-1,still=0,n=0,iv=setInterval(function(){var y=scrollY;still=(y===last)?still+1:0;last=y;if(still>=3||++n>50){clearInterval(iv);fix();}},120);\nif(history.replaceState)history.replaceState(null,'','#consultation');});})();<\/script>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Betaine (trimethylglycine) in cosmetics: INCI, CAS, lab studies, how it differs from the surfactant, and 5 white label formulas to customize.<\/p>\n","protected":false},"author":3,"featured_media":55501,"parent":20287,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-55611","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/carmelcosmeticslabs.com\/en\/wp-json\/wp\/v2\/pages\/55611","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carmelcosmeticslabs.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/carmelcosmeticslabs.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/carmelcosmeticslabs.com\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/carmelcosmeticslabs.com\/en\/wp-json\/wp\/v2\/comments?post=55611"}],"version-history":[{"count":0,"href":"https:\/\/carmelcosmeticslabs.com\/en\/wp-json\/wp\/v2\/pages\/55611\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/carmelcosmeticslabs.com\/en\/wp-json\/wp\/v2\/pages\/20287"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/carmelcosmeticslabs.com\/en\/wp-json\/wp\/v2\/media\/55501"}],"wp:attachment":[{"href":"https:\/\/carmelcosmeticslabs.com\/en\/wp-json\/wp\/v2\/media?parent=55611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}